The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Arfrp1  -  ADP-ribosylation factor related protein 1

Mus musculus

Synonyms: 1500006I01Rik, ADP-ribosylation factor-related protein 1, AI480700, ARF-related protein 1
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Arfrp1


Biological context of Arfrp1

  • Here we describe the organization of the Arfrp1 gene and of its promoter region [3].
  • The Arfrp1 gene spans approximately 7 kb and contains 8 exons [3].

Anatomical context of Arfrp1


Analytical, diagnostic and therapeutic context of Arfrp1

  • Mutational analysis and electrophoretic mobility shift assays indicated that two short cRel- and cEts1-like elements in the 5'-flanking region of Arfrp1 (-76 to -53 and -45 to -23) are critical for the regulation of Arfrp1 expression [3].


  1. Embryonic lethality caused by apoptosis during gastrulation in mice lacking the gene of the ADP-ribosylation factor-related protein 1. Mueller, A.G., Moser, M., Kluge, R., Leder, S., Blum, M., Büttner, R., Joost, H.G., Schürmann, A. Mol. Cell. Biol. (2002) [Pubmed]
  2. Knockout of Arfrp1 leads to disruption of ARF-like1 (ARL1) targeting to the trans-Golgi in mouse embryos and HeLa cells. Zahn, C., Hommel, A., Lu, L., Hong, W., Walther, D.J., Florian, S., Joost, H.G., Sch??rmann, A. Mol. Membr. Biol. (2006) [Pubmed]
  3. Mouse ARF-related protein 1: genomic organization and analysis of its promoter. Mueller, A.G., Joost, H.G., Schürmann, A. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
WikiGenes - Universities