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Gene Review

AT3G05510  -  phospholipid/glycerol acyltransferase...

Arabidopsis thaliana

Synonyms: F22F7.4, F22F7_4
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Disease relevance of AT3G05510


High impact information on AT3G05510

  • The hydroxyl group in the 3-position of the phenylpropanoid compounds is introduced at the level of coumarate shikimate/quinate esters, whose synthesis implicates an acyltransferase activity [2].
  • For functional analysis, the acyltransferase gene was silenced in Arabidopsis thaliana and N. benthamiana by RNA-mediated posttranscriptional gene silencing [2].
  • A loss-of-function mutation in the soluble chloroplastic enzyme glycerol-3-phosphate acyltransferase (ACT1) completely reverses SA- and JA-mediated phenotypes in ssi2 [3].
  • We previously showed that stearoyl-acyl-carrier-protein-desaturase mutants ssi2/fab2 carrying a loss-of-function mutation in the plastidial glycerol-3-phosphate (G3P) acyltransferase (act1) have elevated 18:1 levels and are restored in their altered defense signaling [1].
  • Because G3P is required for the acylation of 18:1 by G3P acyltransferase, it was predicted that reduction of G3P levels should increase 18:1 levels and thereby revert ssi2-triggered phenotypes [1].

Associations of AT3G05510 with chemical compounds

  • In contrast to the act1 mutation, a loss-of-function mutation in the endoplasmic reticulum-localized omega6 oleate desaturase (FAD2) does not alter SA- or JA-related phenotypes of ssi2 [3].
  • We have characterized a member of the BAHD acyltransferase gene family At3g03480 which catalyzes the formation of (Z)-3-hexen-1-yl acetate from acetyl-CoA and (Z)-3-hexen-1-ol [4].


  1. Oleic acid levels regulated by glycerolipid metabolism modulate defense gene expression in Arabidopsis. Kachroo, A., Venugopal, S.C., Lapchyk, L., Falcone, D., Hildebrand, D., Kachroo, P. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  2. Silencing of hydroxycinnamoyl-coenzyme A shikimate/quinate hydroxycinnamoyltransferase affects phenylpropanoid biosynthesis. Hoffmann, L., Besseau, S., Geoffroy, P., Ritzenthaler, C., Meyer, D., Lapierre, C., Pollet, B., Legrand, M. Plant Cell (2004) [Pubmed]
  3. Plastidial fatty acid signaling modulates salicylic acid- and jasmonic acid-mediated defense pathways in the Arabidopsis ssi2 mutant. Kachroo, A., Lapchyk, L., Fukushige, H., Hildebrand, D., Klessig, D., Kachroo, P. Plant Cell (2003) [Pubmed]
  4. Characterization of a BAHD acyltransferase responsible for producing the green leaf volatile (Z)-3-hexen-1-yl acetate in Arabidopsis thaliana. D'Auria, J.C., Pichersky, E., Schaub, A., Hansel, A., Gershenzon, J. Plant J. (2007) [Pubmed]
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