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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SCN1  -  Rho GDP-dissociation inhibitor 1

Arabidopsis thaliana

Synonyms: SUPERCENTIPEDE1
 
 
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High impact information on AT3G07880

  • The results indicated that the interaction between Ara4 and AtGDI1 depends on the conserved C-terminal Cys-motif and Thr44 in the effector domain of Ara4 [1].
  • Recombinant GST-AtRhoGDI1 could bind GFP-AtROP4 from transgenic tobacco BY2 cell extracts, confirming the interaction observed with the two-hybrid system [2].
  • We identified the AtRhoGDI1 gene and mapped it to chromosome 3 [2].
  • AtRhoGDI1 encodes a 22.5 kDa protein which contains highly conserved amino acids in the isoprene binding pocket and exhibits 29% to 37% similarity to known mammalian RhoGDI homologues [2].
  • We have cloned from Arabidopsis thaliana a cDNA coding for the Rab guanosine diphosphate dissociation inhibitor (AtGDI1) by functional complementation of the Saccharomyces cerevisiae sec19-1 mutant [3].
 

Associations of AT3G07880 with chemical compounds

References

  1. Modes of interaction between the Arabidopsis Rab protein, Ara4, and its putative regulator molecules revealed by a yeast expression system. Ueda, T., Matsuda, N., Uchimiya, H., Nakano, A. Plant J. (2000) [Pubmed]
  2. Localization of AtROP4 and AtROP6 and interaction with the guanine nucleotide dissociation inhibitor AtRhoGDI1 from Arabidopsis. Bischoff, F., Vahlkamp, L., Molendijk, A., Palme, K. Plant Mol. Biol. (2000) [Pubmed]
  3. At-GDI1 from Arabidopsis thaliana encodes a rab-specific GDP dissociation inhibitor that complements the sec19 mutation of Saccharomyces cerevisiae. Zárský, V., Cvrcková, F., Bischoff, F., Palme, K. FEBS Lett. (1997) [Pubmed]
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