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ARHGDIA  -  Rho GDP dissociation inhibitor (GDI) alpha

Homo sapiens

Synonyms: GDIA1, HEL-S-47e, NPHS8, RHOGDI, RHOGDI-1, ...
 
 
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Disease relevance of ARHGDIA

 

High impact information on ARHGDIA

 

Biological context of ARHGDIA

 

Anatomical context of ARHGDIA

 

Associations of ARHGDIA with chemical compounds

 

Regulatory relationships of ARHGDIA

 

Other interactions of ARHGDIA

References

  1. Validating the prognostic value of marker genes derived from a non-small cell lung cancer microarray study. Blackhall, F.H., Wigle, D.A., Jurisica, I., Pintilie, M., Liu, N., Darling, G., Johnston, M.R., Keshavjee, S., Waddell, T., Winton, T., Shepherd, F.A., Tsao, M.S. Lung Cancer (2004) [Pubmed]
  2. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. Lang, P., Gesbert, F., Delespine-Carmagnat, M., Stancou, R., Pouchelet, M., Bertoglio, J. EMBO J. (1996) [Pubmed]
  3. The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia. Kozma, R., Ahmed, S., Best, A., Lim, L. Mol. Cell. Biol. (1996) [Pubmed]
  4. Rho GDP dissociation inhibitor protects cancer cells against drug-induced apoptosis. Zhang, B., Zhang, Y., Dagher, M.C., Shacter, E. Cancer Res. (2005) [Pubmed]
  5. Beta8 integrin binds Rho GDP dissociation inhibitor-1 and activates Rac1 to inhibit mesangial cell myofibroblast differentiation. Lakhe-Reddy, S., Khan, S., Konieczkowski, M., Jarad, G., Wu, K.L., Reichardt, L.F., Takai, Y., Bruggeman, L.A., Wang, B., Sedor, J.R., Schelling, J.R. J. Biol. Chem. (2006) [Pubmed]
  6. Human monocytes use Rac1, not Rac2, in the NADPH oxidase complex. Zhao, X., Carnevale, K.A., Cathcart, M.K. J. Biol. Chem. (2003) [Pubmed]
  7. Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI). Fauré, J., Dagher, M.C. Biochimie (2001) [Pubmed]
  8. Comparative proteomic analysis of apoptosis induced by sodium selenite in human acute promyelocytic leukemia NB4 cells. Dong, H., Ying, T., Li, T., Cao, T., Wang, J., Yuan, J., Feng, E., Han, B., Hua, F., Yang, Y., Yuan, J., Wang, H., Xu, C. J. Cell. Biochem. (2006) [Pubmed]
  9. Interaction between Cdc42Hs and RhoGDI is mediated through the Rho insert region. Wu, W.J., Leonard, D.A., A-Cerione, R., Manor, D. J. Biol. Chem. (1997) [Pubmed]
  10. Analysis of differential protein expression in normal and neoplastic human breast epithelial cell lines. Williams, K., Chubb, C., Huberman, E., Giometti, C.S. Electrophoresis (1998) [Pubmed]
  11. Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton. Leffers, H., Nielsen, M.S., Andersen, A.H., Honoré, B., Madsen, P., Vandekerckhove, J., Celis, J.E. Exp. Cell Res. (1993) [Pubmed]
  12. A somatic cell hybrid panel for distal 17q: GDIA1 maps to 17q25.3. Wagner, T., Tommerup, N., Wirth, J., Leffers, H., Zimmer, J., Back, E., Weissenbach, J., Scherer, G. Cytogenet. Cell Genet. (1997) [Pubmed]
  13. An activating mutant of Cdc42 that fails to interact with Rho GDP-dissociation inhibitor localizes to the plasma membrane and mediates actin reorganization. Gibson, R.M., Gandhi, P.N., Tong, X., Miyoshi, J., Takai, Y., Konieczkowski, M., Sedor, J.R., Wilson-Delfosse, A.L. Exp. Cell Res. (2004) [Pubmed]
  14. Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer. Nomanbhoy, T.K., Erickson, J.W., Cerione, R.A. Biochemistry (1999) [Pubmed]
  15. Regulation of the human neutrophil NADPH oxidase by rho-related G-proteins. Kwong, C.H., Malech, H.L., Rotrosen, D., Leto, T.L. Biochemistry (1993) [Pubmed]
  16. Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein. Bowman, E.P., Uhlinger, D.J., Lambeth, J.D. J. Biol. Chem. (1993) [Pubmed]
  17. Proteome alterations in gamma-irradiated human T-lymphocyte leukemia cells. Szkanderová, S., Vávrová, J., Hernychová, L., Neubauerová, V., Lenco, J., Stulík, J. Radiat. Res. (2005) [Pubmed]
  18. Comparative proteomics analysis of the proteins associated with laryngeal carcinoma-related gene 1. Zhang, X., Xiao, Z., Chen, Z., Li, C., Li, J., Yanhui, Y., Yang, F., Yang, Y., Oyang, Y. Laryngoscope (2006) [Pubmed]
  19. GDP dissociation inhibitor D4-GDI (Rho-GDI 2), but not the homologous rho-GDI 1, is cleaved by caspase-3 during drug-induced apoptosis. Essmann, F., Wieder, T., Otto, A., Müller, E.C., Dörken, B., Daniel, P.T. Biochem. J. (2000) [Pubmed]
  20. A truncated tropomyosin-related kinase B receptor, T1, regulates glial cell morphology via Rho GDP dissociation inhibitor 1. Ohira, K., Kumanogoh, H., Sahara, Y., Homma, K.J., Hirai, H., Nakamura, S., Hayashi, M. J. Neurosci. (2005) [Pubmed]
  21. Thiamine transporter gene expression and exogenous thiamine modulate the expression of genes involved in drug and prostaglandin metabolism in breast cancer cells. Liu, S., Stromberg, A., Tai, H.H., Moscow, J.A. Mol. Cancer Res. (2004) [Pubmed]
  22. Comparison of protein expression profiles between monolayer and spheroid cell culture of HT-29 cells revealed fragmentation of CK18 in three-dimensional cell culture. Poland, J., Sinha, P., Siegert, A., Schnölzer, M., Korf, U., Hauptmann, S. Electrophoresis (2002) [Pubmed]
  23. Neutrophil phospholipase D: inhibition by Rho-GDP dissociation inhibitor and stimulation by small GTPase GDP dissociation stimulator. Bowman, E.P., Uhlinger, D.J., Lambeth, J.D. Meth. Enzymol. (1995) [Pubmed]
 
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