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Gene Review

PAS2  -  very-long-chain (3R)-3-hydroxyacyl-[acyl...

Arabidopsis thaliana

Synonyms: F12B17.170, F12B17_170, PASTICCINO 2, PEP, PEPINO
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High impact information on PAS2


Biological context of PAS2


Associations of PAS2 with chemical compounds

  • Abnormal proliferation is enhanced in a mutant background, which elevates endogenous cytokinin levels as seen in double mutants of pepino and altered meristem primordia1 [3].

Other interactions of PAS2

  • This PHYA core region contains two protein-interactive motifs, PAS1 and PAS2 [4].
  • We propose that the PAS2 domain of phytochrome A is necessary to initiate signaling in HIR but not in VLFR, likely via interaction with a specific partner [2].


  1. Arabidopsis PASTICCINO2 is an antiphosphatase involved in regulation of cyclin-dependent kinase A. Da Costa, M., Bach, L., Landrieu, I., Bellec, Y., Catrice, O., Brown, S., De Veylder, L., Lippens, G., Inzé, D., Faure, J.D. Plant Cell (2006) [Pubmed]
  2. Missense mutation in the PAS2 domain of phytochrome A impairs subnuclear localization and a subset of responses. Yanovsky, M.J., Luppi, J.P., Kirchbauer, D., Ogorodnikova, O.B., Sineshchekov, V.A., Adam, E., Kircher, S., Staneloni, R.J., Schäfer, E., Nagy, F., Casal, J.J. Plant Cell (2002) [Pubmed]
  3. The Arabidopsis gene PEPINO/PASTICCINO2 is required for proliferation control of meristematic and non-meristematic cells and encodes a putative anti-phosphatase. Haberer, G., Erschadi, S., Torres-Ruiz, R.A. Dev. Genes Evol. (2002) [Pubmed]
  4. Characterization of a strong dominant phytochrome A mutation unique to phytochrome A signal propagation. Fry, R.C., Habashi, J., Okamoto, H., Deng, X.W. Plant Physiol. (2002) [Pubmed]
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