Disease relevance of NHO1

• Arabidopsis NHO1 is required for general resistance against Pseudomonas bacteria [1].

High impact information on NHO1

• Here, we show that Arabidopsis NHO1, encoding a glycerol kinase, is required for resistance to and induced by Pseudomonas syringae isolates from bean and tobacco [2].
• Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence [2].
• This suppression is abolished in coi1 plants, indicating that DC3000 required an intact jasmonic acid signaling pathway in the plant to suppress NHO1 expression [2].
• A reduction in the NHO1-derived G3P pool also results in a partial age-dependent rescue of the ssi2 morphological and cell death phenotypes in the ssi2 nho1 plants [3].
• GLI1 mapped to chromosome 1 near the putative glycerol kinase gene NHO1 [4].

Biological context of NHO1

• Quantitative RT-PCR analysis showed that GLI1 is expressed in all tissues, but is transiently upregulated during early post-germinative growth and leaf senescence [4].
• Following germination, gli1 seedlings transiently accumulate glycerol derived from the breakdown of storage oil and are more resistant to hyperosmotic stress, salt stress, oxidative stress, freezing and desiccation [4].

Associations of NHO1 with chemical compounds

• Of these, only gli1 is unable to utilise glycerol [4].

References