Gene Review:
LYS4 - homoaconitate hydratase LYS4
Saccharomyces cerevisiae S288c
Synonyms:
Homoaconitase, mitochondrial, Homoaconitate hydratase, LYS3, YD8419.01, YD9934.18, ...
- Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae. Briggs, S.D., Bryk, M., Strahl, B.D., Cheung, W.L., Davie, J.K., Dent, S.Y., Winston, F., Allis, C.D. Genes Dev. (2001)
- Inactivation of homocitrate synthase causes lysine auxotrophy in copper/zinc-containing superoxide dismutase-deficient yeast Schizosaccharomyces pombe. Kwon, E.S., Jeong, J.H., Roe, J.H. J. Biol. Chem. (2006)
- CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. Lee, J.H., Skalnik, D.G. J. Biol. Chem. (2005)
- Ubp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin. Gardner, R.G., Nelson, Z.W., Gottschling, D.E. Mol. Cell. Biol. (2005)
- Cloning and physical characterization of linked lysine genes (lys4, lys15) of Saccharomyces cerevisiae. Wang, L., Okamoto, S., Bhattacharjee, J.K. Curr. Genet. (1989)
- Post-translational processing of rat ribosomal proteins. Ubiquitous methylation of Lys22 within the zinc-finger motif of RL40 (carboxy-terminal extension protein 52) and tissue-specific methylation of Lys4 in RL29. Williamson, N.A., Raliegh, J., Morrice, N.A., Wettenhall, R.E. Eur. J. Biochem. (1997)
- Lysine is synthesized through the alpha-aminoadipate pathway in Thermus thermophilus. Kosuge, T., Hoshino, T. FEMS Microbiol. Lett. (1998)
- MLL Core Components Give the Green Light to Histone Methylation. Crawford, B.D., Hess, J.L. ACS chemical biology (2006)
- Cross-compartment protection by SOD1. Liochev, S.I., Fridovich, I. Free Radic. Biol. Med. (2005)
- Superoxide inhibits 4Fe-4S cluster enzymes involved in amino acid biosynthesis. Cross-compartment protection by CuZn-superoxide dismutase. Wallace, M.A., Liou, L.L., Martins, J., Clement, M.H., Bailey, S., Longo, V.D., Valentine, J.S., Gralla, E.B. J. Biol. Chem. (2004)
- A unique fungal lysine biosynthesis enzyme shares a common ancestor with tricarboxylic acid cycle and leucine biosynthetic enzymes found in diverse organisms. Irvin, S.D., Bhattacharjee, J.K. J. Mol. Evol. (1998)