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Gene Review

SLD2  -  Sld2p

Saccharomyces cerevisiae S288c

Synonyms: DNA replication and checkpoint protein 1, DNA replication regulator SLD2, DRC1, YKL108W, YKL463
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High impact information on SLD2


Biological context of SLD2


Physical interactions of SLD2


Other interactions of SLD2


Analytical, diagnostic and therapeutic context of SLD2


  1. S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast. Masumoto, H., Muramatsu, S., Kamimura, Y., Araki, H. Nature (2002) [Pubmed]
  2. A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11. Tak, Y.S., Tanaka, Y., Endo, S., Kamimura, Y., Araki, H. EMBO J. (2006) [Pubmed]
  3. DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae. Wang, H., Elledge, S.J. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  4. CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast. Tanaka, S., Umemori, T., Hirai, K., Muramatsu, S., Kamimura, Y., Araki, H. Nature (2007) [Pubmed]
  5. Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication. Kamimura, Y., Masumoto, H., Sugino, A., Araki, H. Mol. Cell. Biol. (1998) [Pubmed]
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