Disease relevance of RAB28

• In vegetative tissues, dehydration stress induced rab28 gene expression both in the light and in the dark [1].

High impact information on RAB28

• In this study, we explore the interaction between abscisic acid and VIVIPAROUS1 and its effect on the ABRE from the maize rab28 gene [2].
• A factor that bound to the ABRE in electrophoretic mobility shift assays was present at the same developmental stages as rab28 mRNA and had binding characteristics similar to those observed by in vivo footprinting [2].
• The rab28 gene product accumulated during late embryogenesis [1].
• The spatial and temporal pattern of rab28 mRNA expression during embryogenesis was investigated by in situ hybridization using digoxigenin-labelled rab28 probes, and the immunochemical localization of Rab28 protein using anti-Rab28 antibodies [1].
• Isolation and functional characterisation of two new bZIP maize regulators of the ABA responsive gene rab28 [3].

Chemical compound and disease context of RAB28

• The cis-regulatory element CCACGTGG is involved in ABA and water-stress responses of the maize gene rab28 [4].

Biological context of RAB28

• A novel ras-related gene (rab28) was identified by a PCR-based cloning approach and subsequent screening of rat fat cell and brain cDNA libraries [5].
• Our data suggest that EmBP-2 and ZmBZ-1 are involved in the expression of abscisic acid inducible genes such as rab28 and their activity is modulated by ABA and by phosphorylation [3].

Analytical, diagnostic and therapeutic context of RAB28

• Using immunoelectron microscopy the Rab28 protein has been located in the nucleolus of different cell types [1].

References