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Gene Review

RAB28  -  RAB28, member RAS oncogene family

Homo sapiens

Synonyms: Ras-related protein Rab-28
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Disease relevance of RAB28


High impact information on RAB28

  • In this study, we explore the interaction between abscisic acid and VIVIPAROUS1 and its effect on the ABRE from the maize rab28 gene [2].
  • A factor that bound to the ABRE in electrophoretic mobility shift assays was present at the same developmental stages as rab28 mRNA and had binding characteristics similar to those observed by in vivo footprinting [2].
  • The rab28 gene product accumulated during late embryogenesis [1].
  • The spatial and temporal pattern of rab28 mRNA expression during embryogenesis was investigated by in situ hybridization using digoxigenin-labelled rab28 probes, and the immunochemical localization of Rab28 protein using anti-Rab28 antibodies [1].
  • Isolation and functional characterisation of two new bZIP maize regulators of the ABA responsive gene rab28 [3].

Chemical compound and disease context of RAB28


Biological context of RAB28


Analytical, diagnostic and therapeutic context of RAB28


  1. Expression and cellular localization of rab28 mRNA and Rab28 protein during maize embryogenesis. Niogret, M.F., Culiáñez-Macià, F.A., Goday, A., Mar Albà, M., Pagès, M. Plant J. (1996) [Pubmed]
  2. Protein binding to the abscisic acid-responsive element is independent of VIVIPAROUS1 in vivo. Busk, P.K., Pagès, M. Plant Cell (1997) [Pubmed]
  3. Isolation and functional characterisation of two new bZIP maize regulators of the ABA responsive gene rab28. Nieva, C., Busk, P.K., Domínguez-Puigjaner, E., Lumbreras, V., Testillano, P.S., Risueño, M.C., Pagès, M. Plant Mol. Biol. (2005) [Pubmed]
  4. The cis-regulatory element CCACGTGG is involved in ABA and water-stress responses of the maize gene rab28. Pla, M., Vilardell, J., Guiltinan, M.J., Marcotte, W.R., Niogret, M.F., Quatrano, R.S., Pagès, M. Plant Mol. Biol. (1993) [Pubmed]
  5. Alternative mRNA splicing of the novel GTPase Rab28 generates isoforms with different C-termini. Brauers, A., Schürmann, A., Massmann, S., Mühl-Zürbes, P., Becker, W., Kainulainen, H., Lie, C., Joost, H.G. Eur. J. Biochem. (1996) [Pubmed]
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