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Gene Review

hdeB  -  acid-resistance protein

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3493, JW5669, yhhD, yhiC
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Disease relevance of hdeB


High impact information on hdeB


Chemical compound and disease context of hdeB


Associations of hdeB with chemical compounds

  • Acid resistance system 3 (AR3) is arginine dependent and acid induced under anaerobic conditions, requires the presence of arginine decarboxylase (AdiA), and provides only a modest level of protection [7].


  1. Characterization of enterohemorrhagic Escherichia coli strains based on acid resistance phenotypes. Bhagwat, A.A., Chan, L., Han, R., Tan, J., Kothary, M., Jean-Gilles, J., Tall, B.D. Infect. Immun. (2005) [Pubmed]
  2. Acid resistance in enteric bacteria. Gorden, J., Small, P.L. Infect. Immun. (1993) [Pubmed]
  3. Intracellular Accumulation of Trehalose Protects Lactococcus lactis from Freeze-Drying Damage and Bile Toxicity and Increases Gastric Acid Resistance. Termont, S., Vandenbroucke, K., Iserentant, D., Neirynck, S., Steidler, L., Remaut, E., Rottiers, P. Appl. Environ. Microbiol. (2006) [Pubmed]
  4. Identification of sigma S-dependent genes associated with the stationary-phase acid-resistance phenotype of Shigella flexneri. Waterman, S.R., Small, P.L. Mol. Microbiol. (1996) [Pubmed]
  5. Escherichia coli HdeB Is an Acid Stress Chaperone. Kern, R., Malki, A., Abdallah, J., Tagourti, J., Richarme, G. J. Bacteriol. (2007) [Pubmed]
  6. The glutamate-dependent acid resistance system of Escherichia coli and Shigella flexneri is inhibited in vitro by L-trans-pyrrolidine-2,4-dicarboxylic acid. Waterman, S.R., Small, P.L. FEMS Microbiol. Lett. (2003) [Pubmed]
  7. Acid resistance in Escherichia coli. Richard, H.T., Foster, J.W. Adv. Appl. Microbiol. (2003) [Pubmed]
  8. Evaluation of finishing performance, carcass characteristics, acid-resistant E. coli and total coliforms from steers fed combinations of wet corn gluten feed and steam-flaked corn. Sindt, J.J., Drouillard, J.S., Thippareddi, H., Phebus, R.K., Lambert, D.L., Montgomery, S.P., Farran, T.B., LaBrune, H.J., Higgins, J.J., Ethington, R.T. J. Anim. Sci. (2002) [Pubmed]
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