The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Tchh  -  trichohyalin

Mus musculus

Synonyms: AHF, AI597080, Thh
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Tchh


High impact information on Tchh


Biological context of Tchh


Anatomical context of Tchh

  • BACKGROUND: Recently, in the filiform papillae epithelium of mouse dorsal tongue, we showed the presence of hybrid granules in which filaggrin and trichohyalin were both present, but physically segregated [2].
  • The low-molecular-weight polypeptide factors were obtained from bovine thymus (TF), pineal gland (PF) and anterior hypothalamus (AHF) [6].

Analytical, diagnostic and therapeutic context of Tchh


  1. Immunoelectron microscopy links molecules and morphology in the studies of keratinization. Ishida-Yamamoto, A., Takahashi, H., Iizuka, H. European journal of dermatology : EJD. (2000) [Pubmed]
  2. Expression of keratohyalin-trichohyalin hybrid granules in molluscum contagiosum. Manabe, M., Yaguchi, H., Butt, K.I., O'Guin, W.M., Sun, T.T., Ogawa, H. International journal of dermatology. (1996) [Pubmed]
  3. Identification of human hornerin and its expression in regenerating and psoriatic skin. Takaishi, M., Makino, T., Morohashi, M., Huh, N.H. J. Biol. Chem. (2005) [Pubmed]
  4. Trichohyalin mechanically strengthens the hair follicle: multiple cross-bridging roles in the inner root shealth. Steinert, P.M., Parry, D.A., Marekov, L.N. J. Biol. Chem. (2003) [Pubmed]
  5. Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development. de Jonge, W.J., Hallemeesch, M.M., Kwikkers, K.L., Ruijter, J.M., de Gier-de Vries, C., van Roon, M.A., Meijer, A.J., Marescau, B., de Deyn, P.P., Deutz, N.E., Lamers, W.H. Am. J. Clin. Nutr. (2002) [Pubmed]
  6. Carcinogenesis and aging. IV. Effect of low-molecular-weight factors of thymus, pineal gland and anterior hypothalamus on immunity, tumor incidence and life span of C3H/Sn mice. Anisimov, V.N., Khavinson, V.K., Morozov, V.G. Mech. Ageing Dev. (1982) [Pubmed]
  7. Cytochemistry of trichohyalin granules: a possible role for cornification of inner root sheath cell in the hair follicle. Sugiyama, S. J. Dermatol. (1989) [Pubmed]
  8. The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling. Tobin, D.J., Foitzik, K., Reinheckel, T., Mecklenburg, L., Botchkarev, V.A., Peters, C., Paus, R. Am. J. Pathol. (2002) [Pubmed]
WikiGenes - Universities