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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Communication Disorders

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Disease relevance of Communication Disorders


Psychiatry related information on Communication Disorders


High impact information on Communication Disorders

  • FOXP2, the first gene to have been implicated in a developmental communication disorder, offers a unique entry point into neuromolecular mechanisms influencing human speech and language acquisition [7].
  • The antioxidant N-acetylcysteine (NAC) or placebo was administered in a double-blind fashion to patients who met National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association criteria for probable AD [8].
  • The end point was the development of probable Alzheimer disease according to the criteria of the National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association. RESULTS: Depression was observed in 41 patients (36%) at baseline [9].
  • Autism AKA communication disorder [10].
  • Occurrence of communication disability, situational disability, or satisfactory to poor economic status of the family were the independent predictors of the occurrence of a handicap in children with epilepsy only [11].

Chemical compound and disease context of Communication Disorders

  • To learn more about this approach, a field test was funded by the National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) of the Public Health Service. From 1978 through 1982, the work was planned, carried out, and evaluated by Research Triangle Institute, Research Triangle Park, NC [12].

Biological context of Communication Disorders

  • To investigate this issue, we conducted a retrospective analysis of blood pressures and heart rates of 31 patients 55-85 years of age (mean 69.6) who met National Institute of Neurological and Communicative Disorders and Stroke/Alzheimer Disease and Related Disorders Association criteria for probable AD [13].

Gene context of Communication Disorders


  1. Infarcts of undetermined cause: the NINCDS Stroke Data Bank. Sacco, R.L., Ellenberg, J.H., Mohr, J.P., Tatemichi, T.K., Hier, D.B., Price, T.R., Wolf, P.A. Ann. Neurol. (1989) [Pubmed]
  2. Cognitive-linguistic assessment of individuals with multiple sclerosis. Wallace, G.L., Holmes, S. Archives of physical medicine and rehabilitation. (1993) [Pubmed]
  3. Attention deficit hyperactivity disorder and concomitant communicative disorders. Tetnowski, J.A. Seminars in speech and language. (2004) [Pubmed]
  4. Comparative MR analysis of the entorhinal cortex and hippocampus in diagnosing Alzheimer disease. Juottonen, K., Laakso, M.P., Partanen, K., Soininen, H. AJNR. American journal of neuroradiology. (1999) [Pubmed]
  5. Using a parental checklist to identify diagnostic groups in children with communication impairment: a validation of the Children's Communication Checklist--2. Norbury, C.F., Nash, M., Baird, G., Bishop, D. International journal of language & communication disorders / Royal College of Speech & Language Therapists. (2004) [Pubmed]
  6. ABR and auditory P300 findings in children with ADHD. Schochat, E., Scheuer, C.I., Andrade, E.R. Arquivos de neuro-psiquiatria. (2002) [Pubmed]
  7. Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits. MacDermot, K.D., Bonora, E., Sykes, N., Coupe, A.M., Lai, C.S., Vernes, S.C., Vargha-Khadem, F., McKenzie, F., Smith, R.L., Monaco, A.P., Fisher, S.E. Am. J. Hum. Genet. (2005) [Pubmed]
  8. Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease. Adair, J.C., Knoefel, J.E., Morgan, N. Neurology (2001) [Pubmed]
  9. Depression in patients with mild cognitive impairment increases the risk of developing dementia of Alzheimer type: a prospective cohort study. Modrego, P.J., Ferrández, J. Arch. Neurol. (2004) [Pubmed]
  10. Autism AKA communication disorder. Greenspan, S.I. Journal of the American Academy of Child and Adolescent Psychiatry. (1993) [Pubmed]
  11. Epilepsy in children: prevalence, disability, and handicap. Sillanpää, M. Epilepsia (1992) [Pubmed]
  12. A survey approach for finding cases of epilepsy. Anderson, D.W., Bryan, F.A., Harris, B.S., Lessler, J.T., Gagnon, J.P. Public health reports (Washington, D.C. : 1974) (1985) [Pubmed]
  13. Orthostasis in Alzheimer disease: a retrospective analysis. Jhee, S.S., Sramek, J.J., Wardle, T.S., Cutler, N.R. Alzheimer disease and associated disorders. (1995) [Pubmed]
  14. No association between a presenilin 1 polymorphism and Alzheimer disease. Romas, S.N., Mayeux, R., Tang, M.X., Lantigua, R., Medrano, M., Tycko, B., Knowles, J. Arch. Neurol. (2000) [Pubmed]
  15. Early dramatic recovery during intravenous tissue plasminogen activator infusion: clinical pattern and outcome in acute middle cerebral artery stroke. Felberg, R.A., Okon, N.J., El-Mitwalli, A., Burgin, W.S., Grotta, J.C., Alexandrov, A.V. Stroke (2002) [Pubmed]
  16. Detecting Attention Deficit Hyperactivity Disorder in a communications clinic: diagnostic utility of the Gordon Diagnostic System. Rielly, N.E., Cunningham, C.E., Richards, J.E., Elbard, H.J., Mahoney, W.J. Journal of clinical and experimental neuropsychology : official journal of the International Neuropsychological Society. (1999) [Pubmed]
  17. Speech, language and hearing in Moebius syndrome: a study of 22 patients. Meyerson, M.D., Foushee, D.R. Developmental medicine and child neurology. (1978) [Pubmed]
  18. Early onset sensorineural hearing loss: association studies with major histocompatibility class III (complement) markers. Steuer, M.K., Gross, M., Matthias, R., Mauff, G. The American journal of otology. (1990) [Pubmed]
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