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MeSH Review

Language Disorders

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Disease relevance of Language Disorders


Psychiatry related information on Language Disorders


High impact information on Language Disorders


Chemical compound and disease context of Language Disorders

  • Interruption of nicardipine administration was followed by relapse of the language disorder [12].
  • In order to study the pathophysiology of language disorders due to deep-seated left-hemisphere lesions not involving the cortex, a population of 43 right-handed stroke patients (29 aphasic) presenting with such lesions was studied clinically and by regional cerebral blood flow measurements (two-dimensional xenon-133 inhalation method) [13].
  • Screening for speech and language disorders: the reliability, validity and accuracy of the General Language Screen [14].
  • Audiotaped conversational samples from adults diagnosed as having autistic disorders (n = 15) or developmental receptive language disorders (n = 17) in childhood were transcribed and analyzed using methods based on those of Bishop and Adams (1989) [15].
  • Catabolism of histidine was investigated in 24 patients with different speech and language disorders and with significantly low histidase activity in stratum corneum [16].

Biological context of Language Disorders


Gene context of Language Disorders


  1. Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors. Wang, B., Lin, D., Li, C., Tucker, P. J. Biol. Chem. (2003) [Pubmed]
  2. FOXP2 is not a major susceptibility gene for autism or specific language impairment. Newbury, D.F., Bonora, E., Lamb, J.A., Fisher, S.E., Lai, C.S., Baird, G., Jannoun, L., Slonims, V., Stott, C.M., Merricks, M.J., Bolton, P.F., Bailey, A.J., Monaco, A.P. Am. J. Hum. Genet. (2002) [Pubmed]
  3. Cholinesterases in cerebrospinal fluid. Correlations with clinical measures in Alzheimer's disease. Huff, F.J., Maire, J.C., Growdon, J.H., Corkin, S., Wurtman, R.J. J. Neurol. Sci. (1986) [Pubmed]
  4. A factor analytic study of the Diagnostic Assessment for the Severely Handicapped Scale. Matson, J.L., Coe, D.A., Gardner, W.I., Sovner, R. J. Nerv. Ment. Dis. (1991) [Pubmed]
  5. Gabapentin and methylphenidate treatment of a preadolescent with attention deficit hyperactivity disorder and bipolar disorder. Hamrin, V., Bailey, K. Journal of child and adolescent psychopharmacology. (2001) [Pubmed]
  6. Comorbidity and WISC-III profiles of Greek children with attention deficit hyperactivity disorder, learning disabilities, and language disorders. Filippatou, D.N., Livaniou, E.A. Psychological reports. (2005) [Pubmed]
  7. Localisation of a gene implicated in a severe speech and language disorder. Fisher, S.E., Vargha-Khadem, F., Watkins, K.E., Monaco, A.P., Pembrey, M.E. Nat. Genet. (1998) [Pubmed]
  8. Language fMRI abnormalities associated with FOXP2 gene mutation. Liégeois, F., Baldeweg, T., Connelly, A., Gadian, D.G., Mishkin, M., Vargha-Khadem, F. Nat. Neurosci. (2003) [Pubmed]
  9. MECP2 mutation in a boy with language disorder and schizophrenia. Cohen, D., Lazar, G., Couvert, P., Desportes, V., Lippe, D., Mazet, P., Héron, D. The American journal of psychiatry. (2002) [Pubmed]
  10. Three-dimensional cortical morphometry of the planum temporale in childhood-onset schizophrenia. Jacobsen, L.K., Giedd, J.N., Tanrikut, C., Brady, D.R., Donohue, B.C., Hamburger, S.D., Kumra, S., Alaghband-Rad, J., Rumsey, J.M., Rapoport, J.L. The American journal of psychiatry. (1997) [Pubmed]
  11. Long-term prognosis of poststroke aphasia studied with positron emission tomography. Karbe, H., Kessler, J., Herholz, K., Fink, G.R., Heiss, W.D. Arch. Neurol. (1995) [Pubmed]
  12. Is cerebral arteritis the cause of the Landau-Kleffner syndrome? Four cases in childhood with angiographic study. Pascual-Castroviejo, I., López Martín, V., Martínez Bermejo, A., Pérez Higueras, A. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. (1992) [Pubmed]
  13. Pathogenesis of aphasia in deep-seated lesions: likely role of cortical diaschisis. Demeurisse, G., Capon, A., Verhas, M., Attig, E. Eur. Neurol. (1990) [Pubmed]
  14. Screening for speech and language disorders: the reliability, validity and accuracy of the General Language Screen. Stott, C.M., Merricks, M.J., Bolton, P.F., Goodyer, I.M. International journal of language & communication disorders / Royal College of Speech & Language Therapists. (2002) [Pubmed]
  15. Pragmatic impairments in adults with childhood diagnoses of autism or developmental receptive language disorder. Eales, M.J. Journal of autism and developmental disorders. (1993) [Pubmed]
  16. Disturbances in histidine metabolism in children with speech abnormalities. Pieniazek, D., Kubalska, J., Pronicka, E., Stecko, E. Acta anthropogenetica. (1985) [Pubmed]
  17. FOXP2: novel exons, splice variants, and CAG repeat length stability. Bruce, H.A., Margolis, R.L. Hum. Genet. (2002) [Pubmed]
  18. Identification of the human cortactin-binding protein-2 gene from the autism candidate region at 7q31. Cheung, J., Petek, E., Nakabayashi, K., Tsui, L.C., Vincent, J.B., Scherer, S.W. Genomics (2001) [Pubmed]
  19. The prevalence of the FMR1 and FMR2 mutations among preschool children with language delay. Mazzocco, M.M., Myers, G.F., Hamner, J.L., Panoscha, R., Shapiro, B.K., Reiss, A.L. J. Pediatr. (1998) [Pubmed]
  20. Acquired epileptiform aphasia in children (Landau-Kleffner syndrome). Deonna, T.W. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. (1991) [Pubmed]
  21. An evaluation of screening measures for cognitive impairment after stroke. Blake, H., McKinney, M., Treece, K., Lee, E., Lincoln, N.B. Age and ageing. (2002) [Pubmed]
  22. Dichotic listening performance in subtypes of developmental dyslexia and a left temporal lobe brain tumor contrast group. Cohen, M., Hynd, G., Hugdahl, K. Brain and language. (1992) [Pubmed]
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