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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Genome, Fungal

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Disease relevance of Genome, Fungal


High impact information on Genome, Fungal

  • A survey of 54 fungal genomes revealed that seven other species have proteins with collagenous domains suggesting that MCL1 is a member of a patchily distributed gene family [2].
  • Many plant, animal, and fungal genomes contain cytosine DNA methylation in asymmetric sequence contexts (CpHpH, H = A, T, C) [3].
  • A single copy of a conditional lethal C. neoformans NMT allele was introduced into the fungal genome by homologous recombination [4].
  • Additional naphthalene degradation enzyme-coding genes are present in fungal genomes, suggesting that resistance could follow degradation of the naphthalene ring contained in terbinafine [5].
  • These findings have important implications for fungal genome annotation, as the automated annotations of euascomycete genomes incorrectly identified intron boundaries for all of the confirmed and probable GC-AG introns reported here [6].

Gene context of Genome, Fungal


  1. Agrobacterium-mediated insertional mutagenesis (AIM) of the entomopathogenic fungus Beauveria bassiana. Leclerque, A., Wan, H., Abschütz, A., Chen, S., Mitina, G.V., Zimmermann, G., Schairer, H.U. Curr. Genet. (2004) [Pubmed]
  2. A collagenous protective coat enables Metarhizium anisopliae to evade insect immune responses. Wang, C., St Leger, R.J. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  3. Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes. Cao, X., Jacobsen, S.E. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  4. Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent. Lodge, J.K., Jackson-Machelski, E., Higgins, M., McWherter, C.A., Sikorski, J.A., Devadas, B., Gordon, J.I. J. Biol. Chem. (1998) [Pubmed]
  5. Terbinafine resistance mediated by salicylate 1-monooxygenase in Aspergillus nidulans. Graminha, M.A., Rocha, E.M., Prade, R.A., Martinez-Rossi, N.M. Antimicrob. Agents Chemother. (2004) [Pubmed]
  6. The presence of GC-AG introns in Neurospora crassa and other euascomycetes determined from analyses of complete genomes: implications for automated gene prediction. Rep, M., Duyvesteijn, R.G., Gale, L., Usgaard, T., Cornelissen, B.J., Ma, L.J., Ward, T.J. Genomics (2006) [Pubmed]
  7. Identification of the yeast ACR1 gene product as a succinate-fumarate transporter essential for growth on ethanol or acetate. Palmieri, L., Lasorsa, F.M., De Palma, A., Palmieri, F., Runswick, M.J., Walker, J.E. FEBS Lett. (1997) [Pubmed]
  8. Identification of the yeast ARG-11 gene as a mitochondrial ornithine carrier involved in arginine biosynthesis. Palmieri, L., De Marco, V., Iacobazzi, V., Palmieri, F., Runswick, M.J., Walker, J.E. FEBS Lett. (1997) [Pubmed]
  9. Functional characterisation of glyoxalase I from the fungal wheat pathogen Stagonospora nodorum. Solomon, P.S., Oliver, R.P. Curr. Genet. (2004) [Pubmed]
  10. Molecular analysis of ribosomal DNA from the aphid Amphorophora idaei and an associated fungal organism. Fenton, B., Birch, A.N., Malloch, G., Woodford, J.A., Gonzalez, C. Insect Mol. Biol. (1994) [Pubmed]
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