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MeSH Review:

Blood Patch, Epidural

Bernini, J.C. et al., Chung, S.J. et al., Porter, J. et al., Binder, D.K. et al., McCormack, B.M. et al., et al.

Benzon, Iqbal, Tallman, Boehlke, Russell, Cousins, Brazier, Cook, Binder, Dillon, Fishman, Schmidt, Chung, Lee, Im, Lee,

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Disease relevance of Blood Patch, Epidural

4 of 6 patients with toxic signs and symptoms attributed to methotrexate and unrelieved by steroids, epidural blood patch, promethazine, 5-hydroytryptamine antagonists, paracetamol, and narcotics, had complete resolution of neurotoxicity after or during a 1-h infusion of aminophylline; 2 others had a pronounced improvement but persistent nausea [1].
METHODS: Ten patients with postdural puncture headache presenting for an epidural blood patch were given either saline or sumatriptan subcutaneously [2].
Pseudomeningocele/CSF fistula in a patient with lumbar spinal implants treated with epidural blood patch and a brief course of closed subarachnoid drainage. A case report [3].
In assessing the short-term outcome of CSF hypovolemia, we found that complete headache relief was significantly higher in 43 patients who received epidural blood patch (EBP) than in 10 patients treated with supportive measures (p < 0.05) [4].

High impact information on Blood Patch, Epidural

The efficacy of epidural blood patch in spontaneous CSF leaks [5].
Empirical treatment includes bed rest, administration of caffeine, corticosteroids or mineralocorticoids, epidural blood patch, and epidural saline infusion [6].
Blood mixed with gadolinium was injected, and subsequent MRI scanning provided the first description of spread of blood after cervical epidural blood patch [7].
An epidural blood patch was administered and visualized with tungsten powder [8].
Repeat computed tomographic myelography accomplished via C1-C2 puncture demonstrated a large ventrolateral T1-T3 leak, which was treated successfully with a thoracic epidural blood patch [9].

Biological context of Blood Patch, Epidural

Postpartum seizure after epidural blood patch and intravenous caffeine sodium benzoate [10].

Anatomical context of Blood Patch, Epidural

We hypothesised that the presence of ropivacaine in the epidural space could decrease the efficacy of an epidural blood patch, as this technique requires that the injected blood can clot in order to be effective [11].
Chronic CSF leak into the peritoneal cavity shown by radionuclide cisternography. Successful treatment with an epidural blood patch [12].

Associations of Blood Patch, Epidural with chemical compounds

Sumatriptan: an alternative to epidural blood patch [13]?
An epidural blood patch was performed and enoxaparin was prescribed for 6 months [14].
When the dura was inadvertently punctured during subsequent attempts to inject phenol, immediate epidural blood patch was performed to treat or prevent headache [15].
Levobupivacaine 2.5 mg mL(-1) decreases clot strength and may reduce efficacy of a prophylactic epidural blood patch [16].

Gene context of Blood Patch, Epidural

Treatment with an epidural blood patch reversed his coma within minutes [17].

References

Aminophylline for methotrexate-induced neurotoxicity. Bernini, J.C., Fort, D.W., Griener, J.C., Kane, B.J., Chappell, W.B., Kamen, B.A. Lancet (1995) [Pubmed]
Sumatriptan in patients with postdural puncture headache. Connelly, N.R., Parker, R.K., Rahimi, A., Gibson, C.S. Headache. (2000) [Pubmed]
Pseudomeningocele/CSF fistula in a patient with lumbar spinal implants treated with epidural blood patch and a brief course of closed subarachnoid drainage. A case report. McCormack, B.M., Taylor, S.L., Heath, S., Scanlon, J. Spine. (1996) [Pubmed]
Short- and long-term outcomes of spontaneous CSF hypovolemia. Chung, S.J., Lee, J.H., Im, J.H., Lee, M.C. Eur. Neurol. (2005) [Pubmed]
The efficacy of epidural blood patch in spontaneous CSF leaks. Sencakova, D., Mokri, B., McClelland, R.L. Neurology (2001) [Pubmed]
Headache caused by raised intracranial pressure and intracranial hypotension. Ramadan, N.M. Curr. Opin. Neurol. (1996) [Pubmed]
Intracranial hypotension caused by cervical cerebrospinal fluid leak: treatment with epidural blood patch. Cousins, M.J., Brazier, D., Cook, R. Anesth. Analg. (2004) [Pubmed]
Broadening the clinical spectrum: unusual presentation of spontaneous cerebrospinal fluid hypovolemia. Case report. Nowak, D.A., Rodiek, S.O., Zinner, J., Guhlmann, A., Topka, H. J. Neurosurg. (2003) [Pubmed]
Intrathecal saline infusion in the treatment of obtundation associated with spontaneous intracranial hypotension: technical case report. Binder, D.K., Dillon, W.P., Fishman, R.A., Schmidt, M.H. Neurosurgery (2002) [Pubmed]
Postpartum seizure after epidural blood patch and intravenous caffeine sodium benzoate. Bolton, V.E., Leicht, C.H., Scanlon, T.S. Anesthesiology (1989) [Pubmed]
The effects of ropivacaine hydrochloride on platelet function: an assessment using the platelet function analyser (PFA-100). Porter, J., Crowe, B., Cahill, M., Shorten, G. Anaesthesia. (2001) [Pubmed]
Chronic CSF leak into the peritoneal cavity shown by radionuclide cisternography. Successful treatment with an epidural blood patch. Ashley, D.M., Coleman, R.E., Fuchs, H., Dear, G., Ginsberg, B., Zalduondo, F.M., Friedman, H.S., Longee, D. Clinical nuclear medicine. (1997) [Pubmed]
Sumatriptan: an alternative to epidural blood patch? Lhuissier, C., Mercier, F.J., Dounas, M., Benhamou, D. Anaesthesia. (1996) [Pubmed]
Superior sagittal sinus thrombosis in a patient with postdural puncture headache. Benzon, H.T., Iqbal, M., Tallman, M.S., Boehlke, L., Russell, E.J. Regional anesthesia and pain medicine. (2003) [Pubmed]
Spinal subdural haematoma as a complication of immediate epidural blood patch. Tekkök, I.H., Carter, D.A., Brinker, R. Canadian journal of anaesthesia = Journal canadien d'anesthésie. (1996) [Pubmed]
Evaluation of the effects of levobupivacaine on clotting and fibrinolysis using thromboelastography. Leonard, S.A., Walsh, M., Lydon, A., O'Hare, B., Shorten, G.D. European journal of anaesthesiology. (2000) [Pubmed]
Reversible coma: a rare presentation of spontaneous intracranial hypotension. Kashmere, J.L., Jacka, M.J., Emery, D., Gross, D.W. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. (2004) [Pubmed]

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