High impact information on Corpus Luteum Maintenance

• CONCLUSIONS: VEGF is essential for both the development and maintenance of luteal function [1].
• The present studies show that removal of the pituitary, maintenance of luteal function in hypophysectomized rats with PRL, or acute treatment with prostaglandin F2 alpha had no effect on luteal ATP levels [2].
• Removal of the in situ pituitary on day 0 or 1 resulted in maintenance of luteal function; progesterone concentrations were sustained [3].
• It is concluded from these studies that collagenase and the gelatinases play a role in the tissue remodeling associated with luteal development, proteoglycanase is associated with luteal maintenance, and collagenase may contribute to the structural regression of the corpus luteum [4].
• It is concluded that Prl release is influenced by dopaminergic compounds, and both Prl and LH are required for luteal maintenance in the ferret [5].

Biological context of Corpus Luteum Maintenance

• It also had no effect on the process of luteinization or on the maintenance of luteal function as indicated by the normal levels of plasma and luteal progesterone during pro-oestrus and oestrus during the cycle and in pregnancy [6].
• Furthermore, reduction in the amount of PGF2 alpha released is associated with luteal maintenance and the embryonic signal for maternal recognition of pregnancy must be transmitted before day 10 after ovulation if luteostasis is to be achieved [7].
• In Exp. 2, serum concentration of TIMP-1 did not differ among d 0 to 6 (1.27 +/- .55 microg/mL) of the estrous cycle or among periods of luteal maintenance (1.29 +/- .06 microg/mL), spontaneous luteal regression (1.19 +/- .09 microg/mL), or luteal development (1.22 +/- .08 microg/mL) [8].

Associations of Corpus Luteum Maintenance with chemical compounds

• The results suggest that luteal maintenance in the early pregnant pig is unlikely to be directly due to reduced synthesis of PGF2 alpha [9].
• It is proposed that actinomycin D prevents the increase in uterine PG synthetase levels that normally takes place after Day 11, thereby reducing uterine PGF-2 alpha synthesis and output in vivo, and resulting in luteal maintenance and longer oestrous cycles [10].
• Comparison of intrauterine and subcutaneous sites of estrogen injection for luteal maintenance in swine [11].
• Effects of estradiol benzoate (EB) and zearalenone (Z) on luteal maintenance and plasma hormone concentrations were studied in 45 gilts [12].
• Luteal maintenance during early pregnancy in the pig: role for prostaglandin E2 [13].

Gene context of Corpus Luteum Maintenance

• The role of prolactin in implantation and luteal maintenance in the ferret [14].
• These results indicate that oTP-1 alone is as potent as total conceptus secretory proteins in extending luteal maintenance [15].
• BAX protein was immunolocalized in luteal sections from all stages including luteal rescue but BAX production did not change during luteal maintenance or regression [16].
• The roles of prolactin (Prl) and LH in the maintenance of luteal function in pregnant pigs were investigated [17].
• Administration of recombinant bovine interferon-alpha I at the time of maternal recognition of pregnancy inhibits prostaglandin F2 alpha secretion and causes luteal maintenance in cyclic ewes [18].

References