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MeSH Review:

Vitaceae

Green, M.A. et al., Jeandet, P. et al., Surh, Y.J. et al., DeBolt, S. et al., Yabe, N. et al., et al.

Surh, Chun, Cha, Han, Keum, Park, Lee, Yabe, Matsui, Jeandet, Douillet-Breuil, Bessis, Debord, Sbaghi, Adrian,

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High impact information on Vitaceae

Elucidation of the reactions relating L-tartaric acid to vitamin C catabolism in the Vitaceae showed that they proceed via the oxidation of L-idonic acid, the proposed rate-limiting step in the pathway [1].
Examples are curcumin, a yellow pigment of turmeric (Curcuma longa L., Zingiberaceae), the green tea polyphenol epigallocatechin gallate (EGCG), and resveratrol from grapes (Vitis vinifera, Vitaceae) that strongly suppress tumor promotion [2].
Particular attention has been given here to stilbene phytoalexins produced by Vitaceae, specifically, their pathway of biosynthesis (including stilbene phytoalexin gene transfer experiments to other plants) and their biological activity together with fungal metabolism [3].
In most plants, however (including Vitaceae), ascorbate degradation can occur via dehydroascorbate, yielding oxalate plus L-threonate, with the latter from carbons 3-6 of ascorbate [4].
Ampelopsis brevipedunculata (Vitaceae) extract inhibits a progression of carbon tetrachloride-induced hepatic injury in the mice [5].

Anatomical context of Vitaceae

An ethanol-extract of Ampelopsis brevipedunculata (Vitaceae) berries decreases ferrous iron-stimulated hepatocyte injury in culture [6].

Associations of Vitaceae with chemical compounds

In some plants (Vitaceae), ascorbate is degraded via L-idonate to L-threarate (L-tartrate), with the latter arising from carbons 1-4 of ascorbate [4].

References

L-tartaric acid synthesis from vitamin C in higher plants. DeBolt, S., Cook, D.R., Ford, C.M. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Surh, Y.J., Chun, K.S., Cha, H.H., Han, S.S., Keum, Y.S., Park, K.K., Lee, S.S. Mutat. Res. (2001) [Pubmed]
Phytoalexins from the Vitaceae: biosynthesis, phytoalexin gene expression in transgenic plants, antifungal activity, and metabolism. Jeandet, P., Douillet-Breuil, A.C., Bessis, R., Debord, S., Sbaghi, M., Adrian, M. J. Agric. Food Chem. (2002) [Pubmed]
Vitamin C degradation in plant cells via enzymatic hydrolysis of 4-O-oxalyl-L-threonate. Green, M.A., Fry, S.C. Nature (2005) [Pubmed]
Ampelopsis brevipedunculata (Vitaceae) extract inhibits a progression of carbon tetrachloride-induced hepatic injury in the mice. Yabe, N., Matsui, H. Phytomedicine (2000) [Pubmed]
An ethanol-extract of Ampelopsis brevipedunculata (Vitaceae) berries decreases ferrous iron-stimulated hepatocyte injury in culture. Yabe, N., Tanaka, K., Matsui, H. Journal of ethnopharmacology. (1998) [Pubmed]

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