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Disease relevance of Laurus


High impact information on Laurus


Biological context of Laurus


Associations of Laurus with chemical compounds

  • Anticonvulsant activity of the leaf essential oil of Laurus nobilis against pentylenetetrazole- and maximal electroshock-induced seizures [7].
  • Significant changes due to the irradiation occurred only in (+/-)-linalool and alpha-terpineol, which are typical components of, for example, coriander and bay leaf [8].
  • Almost complete inhibition of 3-nitrotyrosine formation (91% at 300 microg/ml) was achieved only with the essential oil obtained from the leaves of Laurus nobilis [9].
  • The antifungal activity of Aniba rosaeodora, Laurus nobilis, Sassafras albidum and Cinnamomum zeylanicum essential oils were investigated against 17 micromycetes [10].

Gene context of Laurus


  1. Evaluation of the gastroprotective effect of Laurus nobilis seeds on ethanol induced gastric ulcer in rats. Afifi, F.U., Khalil, E., Tamimi, S.O., Disi, A. Journal of ethnopharmacology. (1997) [Pubmed]
  2. Sesquiterpenes (costunolide and zaluzanin D) isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia HL-60 cells. Hibasami, H., Yamada, Y., Moteki, H., Katsuzaki, H., Imai, K., Yoshioka, K., Komiya, T. Int. J. Mol. Med. (2003) [Pubmed]
  3. Optimized and validated HPLC method for alpha- and gamma-tocopherol measurement in Laurus nobilis leaves. New data on tocopherol content. Gómez-Coronado, D.J., Barbas, C. J. Agric. Food Chem. (2003) [Pubmed]
  4. Inhibitory effects of sesquiterpenes from bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction. Matsuda, H., Kagerura, T., Toguchida, I., Ueda, H., Morikawa, T., Yoshikawa, M. Life Sci. (2000) [Pubmed]
  5. Preventive effect of sesquiterpenes from bay leaf on blood ethanol elevation in ethanol-loaded rat: structure requirement and suppression of gastric emptying. Matsuda, H., Shimoda, H., Uemura, T., Yoshikawa, M. Bioorg. Med. Chem. Lett. (1999) [Pubmed]
  6. Inhibitory mechanism of costunolide, a sesquiterpene lactone isolated from Laurus nobilis, on blood-ethanol elevation in rats: involvement of inhibition of gastric emptying and increase in gastric juice secretion. Matsuda, H., Shimoda, H., Ninomiya, K., Yoshikawa, M. Alcohol Alcohol. (2002) [Pubmed]
  7. Anticonvulsant activity of the leaf essential oil of Laurus nobilis against pentylenetetrazole- and maximal electroshock-induced seizures. Sayyah, M., Valizadeh, J., Kamalinejad, M. Phytomedicine (2002) [Pubmed]
  8. The effects of gamma-irradiation on some pure aroma compounds of spices. Sjövall, O., Honkanen, E., Kallio, H., Latva-Kala, K., Sjöberg, A.M. Zeitschrift für Lebensmittel-Untersuchung und -Forschung. (1990) [Pubmed]
  9. Essential oils of commonly used plants as inhibitors of peroxynitrite-induced tyrosine nitration. Chericoni, S., Prieto, J.M., Iacopini, P., Morelli, I. Fitoterapia (2005) [Pubmed]
  10. The chemical composition of some Lauraceae essential oils and their antifungal activities. Simić, A., Soković, M.D., Ristić, M., Grujić-Jovanović, S., Vukojević, J., Marin, P.D. Phytotherapy research : PTR. (2004) [Pubmed]
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