The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Gm14288  -  predicted gene 14288

Mus musculus

Synonyms: OTTMUSG00000016199
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Etohi1


Psychiatry related information on Etohi1


High impact information on Etohi1


Chemical compound and disease context of Etohi1


Biological context of Etohi1


Anatomical context of Etohi1


Associations of Etohi1 with chemical compounds


Physical interactions of Etohi1


Enzymatic interactions of Etohi1


Regulatory relationships of Etohi1


Other interactions of Etohi1


Analytical, diagnostic and therapeutic context of Etohi1


  1. Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors. Crabbe, J.C., Phillips, T.J., Feller, D.J., Hen, R., Wenger, C.D., Lessov, C.N., Schafer, G.L. Nat. Genet. (1996) [Pubmed]
  2. Ethanol-induced chromosomal abnormalities at conception. Kaufman, M.H. Nature (1983) [Pubmed]
  3. Ethanol: modifications of acute intoxication by divalent cations. Erickson, C.K., Tyler, T.D., Harris, R.A. Science (1978) [Pubmed]
  4. Differential contributions of c3, c5, and decay-accelerating factor to ethanol-induced Fatty liver in mice. Pritchard, M.T., McMullen, M.R., Stavitsky, A.B., Cohen, J.I., Lin, F., Medof, M.E., Nagy, L.E. Gastroenterology (2007) [Pubmed]
  5. Differential effects of ethanol antagonism and neuroprotection in peptide fragment NAPVSIPQ prevention of ethanol-induced developmental toxicity. Wilkemeyer, M.F., Chen, S.Y., Menkari, C.E., Brenneman, D.E., Sulik, K.K., Charness, M.E. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  6. An evaluation of the locomotor stimulating action of ethanol in rats and mice. Frye, G.D., Breese, G.R. Psychopharmacology (Berl.) (1981) [Pubmed]
  7. Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity. Crabbe, J.C., Young, E.R., Tam, B., Kosobud, A., Belknap, J.K., Laursen, S.E. J. Pharmacol. Exp. Ther. (1986) [Pubmed]
  8. Involvement of the cholinergic neuronal system and benzodiazepine receptors in alcohol-induced amnesia. Nabeshima, T., Tohyama, K., Ishihara, S., Kameyama, T. Eur. J. Pharmacol. (1991) [Pubmed]
  9. Neurochemical changes in mice following physical or psychological stress exposures. Sutoo, D., Akiyama, K. Behav. Brain Res. (2002) [Pubmed]
  10. LS X SS recombinant inbred strains of mice: initial characterization. DeFries, J.C., Wilson, J.R., Erwin, V.G., Petersen, D.R. Alcohol. Clin. Exp. Res. (1989) [Pubmed]
  11. Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Thiele, T.E., Marsh, D.J., Ste Marie, L., Bernstein, I.L., Palmiter, R.D. Nature (1998) [Pubmed]
  12. Ethanol opens G-protein-activated inwardly rectifying K+ channels. Kobayashi, T., Ikeda, K., Kojima, H., Niki, H., Yano, R., Yoshioka, T., Kumanishi, T. Nat. Neurosci. (1999) [Pubmed]
  13. Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors. Phillips, T.J., Brown, K.J., Burkhart-Kasch, S., Wenger, C.D., Kelly, M.A., Rubinstein, M., Grandy, D.K., Low, M.J. Nat. Neurosci. (1998) [Pubmed]
  14. Early growth response-1 transcription factor is essential for ethanol-induced fatty liver injury in mice. McMullen, M.R., Pritchard, M.T., Wang, Q., Millward, C.A., Croniger, C.M., Nagy, L.E. Gastroenterology (2005) [Pubmed]
  15. Evidence for the involvement of dopamine receptors in ethanol-induced hyperactivity in mice. Cohen, C., Perrault, G., Sanger, D.J. Neuropharmacology (1997) [Pubmed]
  16. Effect of intraperitoneally administered GABA on the locomotor activity of mice. Biswas, B., Carlsson, A. Psychopharmacology (Berl.) (1978) [Pubmed]
  17. Effect of taurine on ethanol-induced changes in open-field locomotor activity. Aragon, C.M., Trudeau, L.E., Amit, Z. Psychopharmacology (Berl.) (1992) [Pubmed]
  18. Behavioral interactions of ethanol and methylxanthines. Dar, M.S., Jones, M., Close, G., Mustafa, S.J., Wooles, W.R. Psychopharmacology (Berl.) (1987) [Pubmed]
  19. Ethanol-induced intracellular calcium mobilization rapidly alters gene expression in the mouse blastocyst. Rout, U.K., Krawetz, S.A., Armant, D.R. Cell Calcium (1997) [Pubmed]
  20. Antagonists of alcohol inhibition of cell adhesion. Wilkemeyer, M.F., Sebastian, A.B., Smith, S.A., Charness, M.E. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  21. Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain. Young, C., Klocke, B.J., Tenkova, T., Choi, J., Labruyere, J., Qin, Y.Q., Holtzman, D.M., Roth, K.A., Olney, J.W. Cell Death Differ. (2003) [Pubmed]
  22. TNF alpha-induced Ras activation due to ethanol promotes hepatocyte proliferation independently of liver injury in the mouse. Isayama, F., Froh, M., Yin, M., Conzelmann, L.O., Milton, R.J., McKim, S.E., Wheeler, M.D. Hepatology (2004) [Pubmed]
  23. Ethanol-induced cell sensitization to bleomycin cytotoxicity and the inhibition of recovery from potentially lethal damage. Mizuno, S. Cancer Res. (1981) [Pubmed]
  24. Role of TNF-alpha in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injury. Ji, C., Deng, Q., Kaplowitz, N. Hepatology (2004) [Pubmed]
  25. Monoclonal antibodies to ethanol-induced rat liver cytochrome P-450 that metabolizes aniline and nitrosamines. Ko, I.Y., Park, S.S., Song, B.J., Patten, C., Tan, Y.Z., Hah, Y.C., Yang, C.S., Gelboin, H.V. Cancer Res. (1987) [Pubmed]
  26. Chronic ethanol treatment increases expression of inhibitory G-proteins and reduces adenylylcyclase activity in the central nervous system of two lines of ethanol-sensitive mice. Wand, G.S., Diehl, A.M., Levine, M.A., Wolfgang, D., Samy, S. J. Biol. Chem. (1993) [Pubmed]
  27. Up-regulation of CD14 in liver caused by acute ethanol involves oxidant-dependent AP-1 pathway. Wheeler, M.D., Thurman, R.G. J. Biol. Chem. (2003) [Pubmed]
  28. An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice. Mansouri, A., Gaou, I., De Kerguenec, C., Amsellem, S., Haouzi, D., Berson, A., Moreau, A., Feldmann, G., Lettéron, P., Pessayre, D., Fromenty, B. Gastroenterology (1999) [Pubmed]
  29. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Ji, C., Kaplowitz, N. Gastroenterology (2003) [Pubmed]
  30. Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver. Bradford, B.U., Kono, H., Isayama, F., Kosyk, O., Wheeler, M.D., Akiyama, T.E., Bleye, L., Krausz, K.W., Gonzalez, F.J., Koop, D.R., Rusyn, I. Hepatology (2005) [Pubmed]
  31. Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome. Deltour, L., Ang, H.L., Duester, G. FASEB J. (1996) [Pubmed]
  32. Effect of leptin administration on membrane-bound adenosine triphosphatase activity in ethanol-induced experimental liver toxicity. Balasubramaniyan, V., Viswanathan, P., Nalini, N. J. Pharm. Pharmacol. (2006) [Pubmed]
  33. The role of alcohol dehydrogenase in retinoic acid homeostasis and fetal alcohol syndrome. Shean, M.L., Duester, G. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. (1993) [Pubmed]
  34. Interaction between RAX and PKR modulates the effect of ethanol on protein synthesis and survival of neurons. Chen, G., Ma, C., Bower, K.A., Ke, Z., Luo, J. J. Biol. Chem. (2006) [Pubmed]
  35. alpha7 Nicotinic acetylcholine receptor knockout selectively enhances ethanol-, but not beta-amyloid-induced neurotoxicity. de Fiebre, N.C., de Fiebre, C.M. Neurosci. Lett. (2005) [Pubmed]
  36. Reduced hypothermic and hypnotic responses to ethanol in PACAP-deficient mice. Tanaka, K., Hashimoto, H., Shintani, N., Yamamoto, A., Baba, A. Regul. Pept. (2004) [Pubmed]
  37. Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain. Maas, J.W., Indacochea, R.A., Muglia, L.M., Tran, T.T., Vogt, S.K., West, T., Benz, A., Shute, A.A., Holtzman, D.M., Mennerick, S., Olney, J.W., Muglia, L.J. J. Neurosci. (2005) [Pubmed]
  38. Genetic factors influence ethanol-induced uroporphyria in Hfe(-/-) mice. Gorman, N., Trask, H.W., Bement, W.J., Szakacs, J.G., Elder, G.H., Balestra, D., Jacobs, N.J., Jacobs, J.M., Sinclair, J.F., Gerhard, G.S., Sinclair, P.R. Hepatology (2004) [Pubmed]
  39. Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid. Deltour, L., Foglio, M.H., Duester, G. J. Biol. Chem. (1999) [Pubmed]
  40. Hydrogen peroxide formation and actin filament reorganization by Cdc42 are essential for ethanol-induced in vitro angiogenesis. Qian, Y., Luo, J., Leonard, S.S., Harris, G.K., Millecchia, L., Flynn, D.C., Shi, X. J. Biol. Chem. (2003) [Pubmed]
  41. Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress. Zhou, Z., Wang, L., Song, Z., Saari, J.T., McClain, C.J., Kang, Y.J. Am. J. Pathol. (2005) [Pubmed]
  42. Endogenous prostaglandin I2 regulates the neural emergency system through release of calcitonin gene related peptide. Arai, K., Ohno, T., Saeki, T., Mizuguchi, S., Kamata, K., Hayashi, I., Saigenji, K., Murata, T., Narumiya, S., Majima, M. Gut (2003) [Pubmed]
  43. Modulation of ethanol-induced central nervous system depression by ibuprofen. Minocha, A., Barth, J.T., Herold, D.A., Gideon, D.A., Spyker, D.A. Clin. Pharmacol. Ther. (1986) [Pubmed]
  44. Ethanol-responsive genes in neural cells include the 78-kilodalton glucose-regulated protein (GRP78) and 94-kilodalton glucose-regulated protein (GRP94) molecular chaperones. Miles, M.F., Wilke, N., Elliot, M., Tanner, W., Shah, S. Mol. Pharmacol. (1994) [Pubmed]
  45. GABA(A) receptors modulate ethanol-induced conditioned place preference and taste aversion in mice. Chester, J.A., Cunningham, C.L. Psychopharmacology (Berl.) (1999) [Pubmed]
  46. Fasting induces impairment of gastric mucosal integrity in non-insulin-dependent diabetic (db/db) mice. Kinoshita, M., Igarashi, S., Kume, E., Saito, N., Arakawa, K. Aliment. Pharmacol. Ther. (2000) [Pubmed]
WikiGenes - Universities