Disease relevance of Matricaria

• Wild chamomile (Matricaria recutita L.) mouthwashes in methotrexate-induced oral mucositis [1].
• Skin prick tests and conjunctival provocation tests also performed in 100 hay fever controls revealed a positive immediate skin response to Artemisia in 15 patients, eight of them also to Matricaria pollen and five of them to Chamomile tea as well [2].

High impact information on Matricaria

• Cross-reactivity among chamomile-tea extract and the pollens of Matricaria chamomilla, Ambrosia trifida (giant ragweed), and Artemisia vulgaris (mugwort), was demonstrated by an ELISA-inhibition study [3].
• Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla [4].
• In the present paper, the lipids contents and ceramide production in the liver and hepatocytes as well as the correction of sphingolipid metabolism at old age using the mixture of Chamomilla recutita flavonoids (chamiloflan) or apigenin-7-glucoside or luteolin-7-glucoside alone have been investigated [5].
• The influence of three compounds of the essential oil of Chamomilla recutita (L.) Rauschert on the protamine sulphate-provoked degranulation of mast cells from Lewis-1a rats was investigated [6].
• Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects [7].

Biological context of Matricaria

• The adult stage of the house fly Musca domestica L. was treated topically with the sublethal doses of LD25, LD50 and LD75 of chamomile, Matricaria chamomilla L. flowers and jasmine, Clerodendron inerme G. leaves oils [8].

Anatomical context of Matricaria

• Effects of some components of the essential oil of chamomile, Chamomilla recutita, on histamine release from rat mast cells [6].

Associations of Matricaria with chemical compounds

• Simultaneous isocratic high-performance liquid chromatographic determination of flavones and coumarins in Matricaria chamonilla extracts [9].
• Quantitative determination of essential oil, total azulenes and chamazulene in German chamomile (Matricaria chamomilla) cultivated in Argentina [10].
• alpha-Bisabolol (BISA) is a sesquiterpene alcohol found in the oils of chamomile (Matricaria chamomilla) and other plants [11].
• Dietary intake of the flower extracts of German chamomile (Matricaria recutita L.) inhibited compound 48/80-induced itch-scratch responses in mice [12].
• The effects on Matricaria recutita L. of an increase of cadmium concentration in soil and in atmosphere were investigated [13].

Gene context of Matricaria

• Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes [14].
• As a result, we discovered a novel and potent NK1 receptor antagonist in the extract of dried flowers of Matricaria chamomilla L [15].

Analytical, diagnostic and therapeutic context of Matricaria

• Validation of a capillary electrophoresis method for the quantitative determination of free and total apigenin in extracts of Chamomilla recutita [16].
• Gas chromatography (GC) and GC-mass spectrometry are used to identify a new sesqiterpene, beta-eudesmol, which seems to be a characteristic essential oil component of the intact and in vitro organized root of chamomile [Chamomilla recutita (L.) Rauschert] [17].

References