High impact information on Dental Pellicle

• Despite its relative inability to interact with precoated SHA, S-IgA1 containing antibody to Ag I/II was readily incorporated into the salivary pellicle during coating, but this did not promote Ag I/II binding [1].
• However, NaSCN was not more effective than NaCl or KCl in desorbing 3H-labeled salivary pellicle components from hydroxyapatite, and NaSCN pretreatment of either strain C5 cells or the salivary pellicles did not destroy or remove either the streptococcal adhesions or the pellicle receptors [2].
• Model delineating the effects of a salivary pellicle on the adsorption of Streptococcus miteor onto hydroxyapatite [3].
• It is postulated that the early sucrose-dependent establishment of S. mutans directly on the enamel pellicle plays a key role in the development of a cariogenic plaque [4].
• Saliva contains acidic proline-rich salivary proteins that are involved in the formation of the salivary pellicle coating supragingival tooth surfaces [5].

Anatomical context of Dental Pellicle

• Salivary protein involvement in the formation of acquired enamel pellicle, so far, has been discussed in terms of hydroxyapatite (HA)-reactive salivary proteins only from the parotid gland [6].

Associations of Dental Pellicle with chemical compounds

• Influence of oral detergents and chlorhexidine on soft-layer electrokinetic parameters of the acquired enamel pellicle [7].
• Salivary pellicle significantly inhibited both microhardness loss, except after 10-min immersion in 1.0% citric acid, and significantly reduced the increase of surface roughness [8].
• The influence of salivary pellicle on enamel acid dissolution by perchloric acid was also assessed by an enamel biopsy method [9].
• Following adsorption of salivary pellicle, six implants from each group were treated with chlorhexidine, stannous fluoride, or sterile saline [10].
• Desorption of acquired enamel pellicle in vivo by pyrophosphate [11].

Gene context of Dental Pellicle

• The possible functional role of heterotypic complexes between MG1 and other salivary proteins as a physiologic delivery system, a mechanism for protection against proteolysis, a repository for precursors of the acquired enamel pellicle, and a vehicle for modulation of the viscoelastic and rheological properties of saliva is discussed [12].
• The presence of active CA VI in the human enamel pellicle suggests that it may accelerate the removal of acid by functioning locally in the pellicle layer on dental surfaces [13].
• Immunochemical identification and determination of proline-rich proteins in salivary secretions, enamel pellicle, and glandular tissue specimens [14].
• Several functional properties of MG1, MG2, and PRG have been examined, including their presence in two-hour in vivo enamel pellicle, binding to synthetic hydroxyapatite, lubricating properties, and interactions with oral streptococci [15].
• Recently, we demonstrated that anti-statherin monoclonal antibodies could be generated upon immunisation of mice with in vivo formed human acquired enamel pellicle, indicating that statherin is a constituent of pellicle [16].

Analytical, diagnostic and therapeutic context of Dental Pellicle

• Electron microscopy has described the salivary pellicle as an 'uneven, knotted structure'. This study describes a novel soft-layer model of salivary pellicles, based on measured electrophoretic mobilities and the influence of dentifrices and a chlorhexidine mouthwash on the parameters of the model [7].
• The aim of this study was to investigate the quantitative composition and individual variation of the salivary pellicle formed on denture base material (PMMA) [17].
• Salivary proteins and glycoproteins that participate in the formation of 2-h in vivo enamel pellicle were determined utilizing polyacrylamide gel electrophoresis [sodium dodecyl sulphate (SDS)-PAGE and anionic PAGE]/Western transfer analyses, and specific radiolabelling/SDS-PAGE fluorography [18].

References