Disease relevance of Colitis, Lymphocytic

• Drug induced disease was suspected for ticlopidine (two collagenous colitis, four lymphocytic colitis) and flutamide (four lymphocytic colitis) [1].
• We report a case of interstitial pulmonary disease that occurred together with lymphocytic colitis during treatment with ticlopidine [2].
• The aim of our study was to determine the prevalence of celiac disease in microscopic colitis (collagenous and lymphocytic colitis) [3].
• One patient with lymphocytic colitis demonstrated both elevated titres of tTG antibody and positive EmA, and small bowel biopsy confirmed celiac disease [4].
• Chronic lymphocytic-plasmacytic colitis was found in 54.6% (47 out of 86), chronic ulcerative colitis in 15.1% (13 out of 86), Crohn's colitis in 12.8% (11 out of 86), superficial lymphocytic colitis in 10.5% (9 out of 86), cryptal lymphocytic colitis in 5.8% (5 out of 86) and collagenous colitis in 1.2% (1 out of 86) [5].

High impact information on Colitis, Lymphocytic

• We report a case of lymphocytic colitis induced by acarbose [6].
• Ranitidine, diarrhoea, and lymphocytic colitis [7].
• Nonsteroidal antiinflammatory drugs, cyclo 3 fort, flutamide, lansoprazole, and ticlopidine are associated with lymphocytic colitis [8].
• Colonic histopathology in some patients with untreated celiac sprue and refractory sprue has been said to be indistinguishable from lymphocytic colitis, but there have been no objective comparisons on which this is based [9].
• CONCLUSIONS: There are clear differences, with respect to extracellular matrix remodelling, between collagenous and lymphocytic colitis [10].

Chemical compound and disease context of Colitis, Lymphocytic

• Interestingly, a case of cryptal lymphocytic colitis was recently recorded in a non-human primate dying after years of protracted chronic diarrhoea [11].
• Azathioprine as a treatment of refractory lymphocytic colitis [12].
• Luminal nitric oxide and epithelial expression of inducible and endothelial nitric oxide synthase in collagenous and lymphocytic colitis [13].

Biological context of Colitis, Lymphocytic

• Celiac disease was identified in 4 patients by small bowel histology; all had lymphocytic colitis (4 of 27 patients, 15%) [3].

Gene context of Colitis, Lymphocytic

• Limited information is available on the frequency of celiac disease in lymphocytic colitis [3].
• The aim of this study was to investigate colonic NO levels in patients with CC and lymphocytic colitis (LC), to compare with the histopathological status and with the clinical activity, and to assess the epithelial expression of inducible and endothelial nitric oxide synthase (iNOS and eNOS) [13].
• Twelve of 25 (48%) patients with lymphocytic colitis (P = 0.027 versus controls), and 11 of 34 (32.3%) with collagenous colitis (P = 0.38 versus controls) were DQ2-positive [14].

References