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Psychiatry related information on Grooming


High impact information on Grooming

  • One hour after the light was switched on, physiological saline, (+)-amphetamine 1 mg/kg, and H 77/77 5 mg/kg were injected s.c.; the number of groomings was counted 1-2 h after the treatments [2].
  • The effects of intracerebroventricular injections of 8-OH-DPAT (a 5-HT1A agonist; 3, 15 or 30 nmol) or GR46611 (a 5-HT1B/1D agonist; 3, 15 or 30 nmol) on feeding, drinking, preening and sleep-like behaviors were investigated in free-feeding (FF) pigeons [3].
  • PGE(2) at 0.1, 1.0 and 3.2 microg (per animal; i.c.v.) given prior to SR141716A (10 mg/kg, i.p.) dose-dependently decreased the number of forepaw licking, facial preening, grooming and forepaw tremor episodes [4].
  • Chicks given NPY or PYY also spent significantly less time standing while those given PYY spent significantly less time preening compared to controls [5].
  • Thyrotropin-releasing hormone (TRH) injected i.p. in doses of 5 mg/kg and higher had a strong locomotor stimulant action with development of frequent rearing, mild sniffing, grooming, preening and other excitatory behaviours [6].

Chemical compound and disease context of Grooming

  • Effects on environmentally induced oral stereotypies (object pecking and drinker-directed activity) and other behavior (sitting, standing, pacing, preening), of preferential antagonists and agonists of central 5-HT and GABA receptor subtypes, were examined in individually caged broiler breeder fowls subjected to chronic food restriction [7].
  • The sedation, increased yawning, and decreased preening induced by the two DA agonists were reversed by the D2-selective antagonist, sulpiride [8].
  • With 5-HT agonists, 8-OH-DPAT (5-HT1A) suppressed the two oral stereotypies and increased standing (all 1.0 mg/kg) and preening (0.2 mg/kg), alpha-methylserotonin (5-HT2) suppressed the oral stereotypies and increased sitting (all 1.0 mg/kg), and m-CPBG (5-HT3) suppressed drinker-directed activity (1.0 mg/kg) [7].
  • Effects on feeding, drinking, and preening were similar after AVT injection into the lateral ventricles, but the central effects were not blocked by dPTyr(Me)AVP, a selective AVT receptor blocker [9].
  • The GABA antagonists (bicuculline (GABAA), 5-aminovaleric acid (GABAB) had no effect, and of the GABA agonists [muscimol (GABAA), baclofen (GABAB)], muscimol suppressed preening and increased sitting, standing (all 1.0 mg/kg), and pacing (0.2 mg/kg) [7].

Gene context of Grooming

  • Stepping and wing flapping were increased dose-dependently, but OT decreased preening [10].
  • On the other hand, treatment of intact rats with the 5-HT1A receptor agonist ipsapirone (2.5 mg/kg), a drug that also decreases ethanol drinking in two-bottle intake tests, did increase the duration of aversive groomings, whereas measures of ingestion remained unaffected [11].

Analytical, diagnostic and therapeutic context of Grooming


  1. Antianxiety effects of riparin I from Aniba riparia (Nees) Mez (Lauraceae) in mice. de Sousa, F.C., Monteiro, A.P., de Melo, C.T., de Oliveira, G.R., Vasconcelos, S.M., de França Fonteles, M.M., Gutierrez, S.J., Barbosa-Filho, J.M., Viana, G.S. Phytotherapy research : PTR. (2005) [Pubmed]
  2. Evidence for a noradrenergic mechanism in the grooming produced by (+)-amphetamine and 4, alpha-dimethyl-m-tyramine (H 77/77) in rats. Lassen, J.B. Psychopharmacology (Berl.) (1977) [Pubmed]
  3. Ingestive behaviors and metabolic fuels after central injections of 5-HT1A and 5-HT1D/1B receptors agonists in the pigeon. Da Silva, R.A., de Oliveira, S.T., Hackl, L.P., Spilere, C.I., Faria, M.S., Marino-Neto, J., Paschoalini, M.A. Brain Res. (2004) [Pubmed]
  4. Prostaglandin E2 attenuates SR141716A-precipitated withdrawal in tetrahydrocannabinol-dependent mice. Anggadiredja, K., Yamaguchi, T., Tanaka, H., Shoyama, Y., Watanabe, S., Yamamoto, T. Brain Res. (2003) [Pubmed]
  5. Robust feeding following central administration of neuropeptide Y or peptide YY in chicks, Gallus domesticus. Kuenzel, W.J., Douglass, L.W., Davison, B.A. Peptides (1987) [Pubmed]
  6. Mesolimbic involvement in the locomotor stimulant action of thyrotropin-releasing hormone (TRH) in rats. Miyamoto, M., Nagawa, Y. Eur. J. Pharmacol. (1977) [Pubmed]
  7. Behavioral responses of restricted-fed fowls to pharmacological manipulation of 5-HT and GABA receptor subtypes. Kostal, L., Savory, C.J. Pharmacol. Biochem. Behav. (1996) [Pubmed]
  8. Behavioural profile in the chicken of CQ 32-084 and CQP 201-403, two dopamine agonists. Ferrari, F., Pelloni, F., Giuliani, D. Pharmacol. Biochem. Behav. (1993) [Pubmed]
  9. A potential cardiovascular mechanism for the behavioral effects of central and peripheral arginine vasotocin. Nephew, B.C., Reed, L.M., Romero, L.M. Gen. Comp. Endocrinol. (2005) [Pubmed]
  10. Behavioral effects of intracerebroventricular injection of oxytocin in birds. Jonaidi, H., Oloumi, M.M., Denbow, D.M. Physiol. Behav. (2003) [Pubmed]
  11. Taste reactivity to ethanol in rats: influence of adrenalectomy or ipsapirone. Fahlke, C., Thomasson, R., Hård, E., Engel, J.A., Hansen, S. Alcohol (1994) [Pubmed]
  12. Regional alterations in the monoamine levels, monoamine oxidase activity & neurobehavioural effects in rats treated with Dimecron (phosphamidon). Naqvi, S.M., Hasan, M. Indian J. Med. Res. (1991) [Pubmed]
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