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Chemical Compound Review

CHEMBL281497     3-(1-aminopropan-2-yl)-1H- indol-5-ol

Synonyms: SureCN7640404, AC1L3GVW, LS-173969, PDSP1_001681, PDSP2_001664, ...
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Disease relevance of alpha-Methylserotonin


Psychiatry related information on alpha-Methylserotonin

  • The serotonergic agonists quipazine, CGS-12066A, and alpha-methylserotonin alter motor activity and induce hindlimb stepping in the intact and spinal rat fetus [2].
  • With 5-HT agonists, 8-OH-DPAT (5-HT1A) suppressed the two oral stereotypies and increased standing (all 1.0 mg/kg) and preening (0.2 mg/kg), alpha-methylserotonin (5-HT2) suppressed the oral stereotypies and increased sitting (all 1.0 mg/kg), and m-CPBG (5-HT3) suppressed drinker-directed activity (1.0 mg/kg) [3].

High impact information on alpha-Methylserotonin


Biological context of alpha-Methylserotonin


Anatomical context of alpha-Methylserotonin


Associations of alpha-Methylserotonin with other chemical compounds


Gene context of alpha-Methylserotonin


Analytical, diagnostic and therapeutic context of alpha-Methylserotonin


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  2. The serotonergic agonists quipazine, CGS-12066A, and alpha-methylserotonin alter motor activity and induce hindlimb stepping in the intact and spinal rat fetus. Brumley, M.R., Robinson, S.R. Behav. Neurosci. (2005) [Pubmed]
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  16. The endothelium contributes to the contractile responses of the human umbilical artery to 5-hydroxytryptamine and endothelin-1 under low but not high PO2 conditions. Xie, H., Triggle, C.R. Can. J. Physiol. Pharmacol. (1994) [Pubmed]
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  22. Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice. Yamaguchi, T., Nagasawa, T., Satoh, M., Kuraishi, Y. Neurosci. Res. (1999) [Pubmed]
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