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Disease relevance of Loiasis


High impact information on Loiasis


Chemical compound and disease context of Loiasis

  • The importance of the 29-31 kDa glycoprotein in the immunobiology of loaiasis is suggested by the finding that resistant and infected amicrofilaremic individuals have strongly reactive IgG antibodies to this antigen [7].
  • Species-specific sequence in the repeat 3 region of the gene encoding a putative Loa loa allergen: a diagnostic tool for occult loiasis [8].

Gene context of Loiasis


Analytical, diagnostic and therapeutic context of Loiasis


  1. Five cases of encephalitis during treatment of loiasis with diethylcarbamazine. Carme, B., Boulesteix, J., Boutes, H., Puruehnce, M.F. Am. J. Trop. Med. Hyg. (1991) [Pubmed]
  2. Diethylcarbamazine and human loiasis. Jaccard, A., Lortholary, O., Visser, H. N. Engl. J. Med. (1989) [Pubmed]
  3. Mebendazole treatment of loaiasis. Van Hoegaerden, M., Flocard, F. Lancet (1985) [Pubmed]
  4. Identification of a surface antigen on Loa loa microfilariae the recognition of which correlates with the amicrofilaremic state in man. Pinder, M., Dupont, A., Egwang, T.G. J. Immunol. (1988) [Pubmed]
  5. Doxycycline and eradication of microfilaremia in patients with loiasis. Brouqui, P., Fournier, P.E., Raoult, D. Emerging Infect. Dis. (2001) [Pubmed]
  6. Albendazole in human loiasis: results of a double-blind, placebo-controlled trial. Klion, A.D., Massougbodji, A., Horton, J., Ekoué, S., Lanmasso, T., Ahouissou, N.L., Nutman, T.B. J. Infect. Dis. (1993) [Pubmed]
  7. The identification and partial characterization of an immunodominant 29-31 kilodalton surface antigen expressed by adult worms of the human filaria Loa loa. Egwang, T.G., Akué, J.P., Dupont, A., Pinder, M. Mol. Biochem. Parasitol. (1988) [Pubmed]
  8. Species-specific sequence in the repeat 3 region of the gene encoding a putative Loa loa allergen: a diagnostic tool for occult loiasis. Toure, F.S., Egwang, T.G., Wahl, G., Millet, P., Bain, O., Georges, A.J. Am. J. Trop. Med. Hyg. (1997) [Pubmed]
  9. Human occult loiasis: improvement in diagnostic sensitivity by the use of a nested polymerase chain reaction. Touré, F.S., Kassambara, L., Williams, T., Millet, P., Bain, O., Georges, A.J., Egwang, T.G. Am. J. Trop. Med. Hyg. (1998) [Pubmed]
  10. Clinical and biological study of Loa loa filariasis in Congolese. Carme, B., Mamboueni, J.P., Copin, N., Noireau, F. Am. J. Trop. Med. Hyg. (1989) [Pubmed]
  11. Diethylcarbamazine prophylaxis for human loiasis. Results of a double-blind study. Nutman, T.B., Miller, K.D., Mulligan, M., Reinhardt, G.N., Currie, B.J., Steel, C., Ottesen, E.A. N. Engl. J. Med. (1988) [Pubmed]
  12. Effectiveness of diethylcarbamazine in treating loiasis acquired by expatriate visitors to endemic regions: long-term follow-up. Klion, A.D., Ottesen, E.A., Nutman, T.B. J. Infect. Dis. (1994) [Pubmed]
  13. Biochemical and immunochemical characterization of surface and excretory-secretory antigens of Loa loa microfilariae. Egwang, T.G., Dupont, A., Akué, J.P., Pinder, M. Mol. Biochem. Parasitol. (1988) [Pubmed]
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