Psychiatry related information on Salidroside

• Day 1: One hour after acute Rhodiola rosea intake (R, 200-mg Rhodiola rosea extract containing 3% rosavin + 1% salidroside plus 500 mg starch) or placebo (P, 700 mg starch) speed of limb movement (plate tapping test), aural and visual reaction time, and the ability to sustain attention (Fepsy Vigilance test) were assessed [1].

High impact information on Salidroside

• The enzyme named salidroside mono-oxygenase required NADPH as the only cofactor, and molecular oxygen [2].
• The crude salidroside was obtained by extraction with methanol from Rhodiola sachalinensis A [3].
• The kinetics of dry weight accumulation and cellular salidroside content in various culture conditions for the strain was determined [4].
• The corresponding salidroside yield was 555.13 mg l-1, a level suitable for cost effective commercial production to compensate the natural resource shortage of R. sachalinensis [4].
• Quantitative determination of salidroside and specnuezhenide in the fruits of Ligustrum lucidum Ait by high performance liquid chromatography [5].

Anatomical context of Salidroside

• In conclusion, salidroside may protect PC12 cell against glutamate excitotoxic damage through suppressing the excessive entry of Ca2+ and the release of the calcium stores [6].
• To confirm and extend results obtained in the few preclinical and clinical studies available in English language journals, the purpose of the present study was to re-investigate the effects produced by a single oral administration of an R. rosea hydroalcohol extract (containing 3% rosavin and 1% salidroside) on the central nervous system in mice [7].

Associations of Salidroside with other chemical compounds

• The effect of salidroside on cell damage induced by glutamate and intracellular free calcium in PC12 cells [6].
• In present experiment, salidroside could protect the PC12 cell against injuries caused by exposure of PC12 cells to 2 mmol/L glutamate for 15 min followed by incubation with serum-free medium for 24 h, which resembled the excitotoxin in vivo system [6].
• Quantitative determination of salidroside and tyrosol from the underground part of Rhodiola rosea by high performance liquid chromatography [8].
• X-ray crystal structure and antioxidant activity of salidroside, a phenylethanoid glycoside [9].

Analytical, diagnostic and therapeutic context of Salidroside

• The method yielded 21.9 mg of salidroside from 1.216 g of the crude sample at 98% purity determined by HPLC analyses [10].
• Salidroside (Sald), was extracted from Rhodiola rosea L, a traditional Chinese medicine which has been used for long time for anti-aging, anti-cancer and anti-oxidative stress etc [6].

References