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Chemical Compound Review

Rhodosin     (2R,3S,4S,5R,6R)-2- (hydroxymethyl)-6-[2-(4...

Synonyms: Salidroside, Rhodioloside, S2396_Selleck, CHEMBL465208, SureCN148079, ...
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Psychiatry related information on Salidroside

  • Day 1: One hour after acute Rhodiola rosea intake (R, 200-mg Rhodiola rosea extract containing 3% rosavin + 1% salidroside plus 500 mg starch) or placebo (P, 700 mg starch) speed of limb movement (plate tapping test), aural and visual reaction time, and the ability to sustain attention (Fepsy Vigilance test) were assessed [1].

High impact information on Salidroside


Anatomical context of Salidroside

  • In conclusion, salidroside may protect PC12 cell against glutamate excitotoxic damage through suppressing the excessive entry of Ca2+ and the release of the calcium stores [6].
  • To confirm and extend results obtained in the few preclinical and clinical studies available in English language journals, the purpose of the present study was to re-investigate the effects produced by a single oral administration of an R. rosea hydroalcohol extract (containing 3% rosavin and 1% salidroside) on the central nervous system in mice [7].

Associations of Salidroside with other chemical compounds


Analytical, diagnostic and therapeutic context of Salidroside


  1. Acute Rhodiola rosea intake can improve endurance exercise performance. De Bock, K., Eijnde, B.O., Ramaekers, M., Hespel, P. International journal of sport nutrition and exercise metabolism. (2004) [Pubmed]
  2. Formation of benzoquinol moiety in cornoside by salidroside mono-oxygenase, a cytochrome P450 enzyme, from Abeliophyllum distichumcell suspension cultures. Yamamoto, H., Hori, M., Kuwajima, H., Inoue, K. Planta (2003) [Pubmed]
  3. Preparative isolation and purification of salidroside from the Chinese medicinal plant Rhodiola sachalinensis by high-speed counter-current chromatography. Li, H.B., Chen, F. Journal of chromatography. A. (2001) [Pubmed]
  4. High yield production of salidroside in the suspension culture of Rhodiola sachalinensis. Wu, S., Zu, Y., Wu, M. J. Biotechnol. (2003) [Pubmed]
  5. Quantitative determination of salidroside and specnuezhenide in the fruits of Ligustrum lucidum Ait by high performance liquid chromatography. Shi, L., Ma, Y., Cai, Z. Biomed. Chromatogr. (1998) [Pubmed]
  6. The effect of salidroside on cell damage induced by glutamate and intracellular free calcium in PC12 cells. Cao, L.L., Du, G.H., Wang, M.W. Journal of Asian natural products research. (2006) [Pubmed]
  7. Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice. Perfumi, M., Mattioli, L. Phytotherapy research : PTR (2007) [Pubmed]
  8. Quantitative determination of salidroside and tyrosol from the underground part of Rhodiola rosea by high performance liquid chromatography. Linh, P.T., Kim, Y.H., Hong, S.P., Jian, J.J., Kang, J.S. Arch. Pharm. Res. (2000) [Pubmed]
  9. X-ray crystal structure and antioxidant activity of salidroside, a phenylethanoid glycoside. Yu, P., Hu, C., Meehan, E.J., Chen, L. Chem. Biodivers. (2007) [Pubmed]
  10. Separation of salidroside from Rhodiola crenulata by high-speed counter-current chromatography. Han, X., Zhang, T., Wei, Y., Cao, X., Ito, Y. Journal of chromatography. A. (2002) [Pubmed]
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