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Chemical Compound Review

Octogen     1,3,5,7-tetranitro-1,3,5,7- tetrazocane

Synonyms: Oktogen, beta-Hmy, HW 4, CHEBI:33176, HSDB 5893, ...
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Disease relevance of Tetramethylenetetranitramine


High impact information on Tetramethylenetetranitramine


Biological context of Tetramethylenetetranitramine


Associations of Tetramethylenetetranitramine with other chemical compounds


Analytical, diagnostic and therapeutic context of Tetramethylenetetranitramine


  1. Isolation of three hexahydro-1,3,5-trinitro-1,3,5-triazine-degrading species of the family Enterobacteriaceae from nitramine explosive-contaminated soil. Kitts, C.L., Cunningham, D.P., Unkefer, P.J. Appl. Environ. Microbiol. (1994) [Pubmed]
  2. Chronic toxicity of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) in soil determined using the earthworm (Eisenia andrei) reproduction test. Robidoux, P.Y., Hawari, J., Thiboutot, S., Ampleman, G., Sunahara, G.I. Environ. Pollut. (2001) [Pubmed]
  3. Metabolism of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine by Clostridium bifermentans strain HAW-1 and several other H2-producing fermentative anaerobic bacteria. Zhao, J.S., Paquet, L., Halasz, A., Manno, D., Hawari, J. FEMS Microbiol. Lett. (2004) [Pubmed]
  4. Acute occupational poisoning by octogen: first case report. Testud, F., Descotes, J., Le Meur, B. Clinical toxicology (Philadelphia, Pa.) (2006) [Pubmed]
  5. Metabolism of the aliphatic nitramine 4-nitro-2,4-diazabutanal by Methylobacterium sp. strain JS178. Fournier, D., Trott, S., Hawari, J., Spain, J. Appl. Environ. Microbiol. (2005) [Pubmed]
  6. Mechanism of xanthine oxidase catalyzed biotransformation of HMX under anaerobic conditions. Bhushan, B., Paquet, L., Halasz, A., Spain, J.C., Hawari, J. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  7. Biodegradation of the nitramine explosives hexahydro-1,3,5-trinitro-1,3,5-triazine and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine in cold marine sediment under anaerobic and oligotrophic conditions. Zhao, J.S., Greer, C.W., Thiboutot, S., Ampleman, G., Hawari, J. Can. J. Microbiol. (2004) [Pubmed]
  8. Biotransformation routes of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine by municipal anaerobic sludge. Hawari, J., Halasz, A., Beaudet, S., Paquet, L., Ampleman, G., Thiboutot, S. Environ. Sci. Technol. (2001) [Pubmed]
  9. Reductive transformation of hexahydro-1,3,5-trinitro-1,3,5-triazine, octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine, and methylenedinitramine with elemental iron. Oh, S.Y., Cha, D.K., Kim, B.J., Chiu, P.C. Environ. Toxicol. Chem. (2005) [Pubmed]
  10. Reduction of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine by zerovalent iron: product distribution. Monteil-Rivera, F., Paquet, L., Halasz, A., Montgomery, M.T., Hawari, J. Environ. Sci. Technol. (2005) [Pubmed]
  11. Alkaline hydrolysis of the cyclic nitramine explosives RDX, HMX, and CL-20: new insights into degradation pathways obtained by the observation of novel intermediates. Balakrishnan, V.K., Halasz, A., Hawari, J. Environ. Sci. Technol. (2003) [Pubmed]
  12. Liquid chromatography/electrospray ionization tandem mass spectrometry analysis of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX). Pan, X., Zhang, B., Tian, K., Jones, L.E., Liu, J., Anderson, T.A., Wang, J.S., Cobb, G.P. Rapid Commun. Mass Spectrom. (2006) [Pubmed]
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