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Chemical Compound Review

Cyclonit     1,3,5-trinitro-1,3,5- triazinane

Synonyms: Cyklonit, Geksogen, Heksogen, Hexogeen, Hexolite, ...
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Disease relevance of Hexogeen


High impact information on Hexogeen


Chemical compound and disease context of Hexogeen


Biological context of Hexogeen


Anatomical context of Hexogeen


Associations of Hexogeen with other chemical compounds


Gene context of Hexogeen


Analytical, diagnostic and therapeutic context of Hexogeen

  • Idiopathic RF (2/3 of cases) must be distinguished from secondary RF, caused by hexogen substances assumptions, radiotherapy and various diseases [28].
  • ABSTRACT : BACKGROUND : Cell culture systems are useful in studying toxicological effects of chemicals such as Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), however little is known as to how accurately isolated cells reflect responses of intact organs [29].


  1. An explosive-degrading cytochrome P450 activity and its targeted application for the phytoremediation of RDX. Rylott, E.L., Jackson, R.G., Edwards, J., Womack, G.L., Seth-Smith, H.M., Rathbone, D.A., Strand, S.E., Bruce, N.C. Nat. Biotechnol. (2006) [Pubmed]
  2. Determination of key metabolites during biodegradation of hexahydro-1,3,5-trinitro-1,3,5-triazine with Rhodococcus sp. strain DN22. Fournier, D., Halasz, A., Spain, J., Fiurasek, P., Hawari, J. Appl. Environ. Microbiol. (2002) [Pubmed]
  3. Isolation of three hexahydro-1,3,5-trinitro-1,3,5-triazine-degrading species of the family Enterobacteriaceae from nitramine explosive-contaminated soil. Kitts, C.L., Cunningham, D.P., Unkefer, P.J. Appl. Environ. Microbiol. (1994) [Pubmed]
  4. Degradation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) by Stenotrophomonas maltophilia PB1. Binks, P.R., Nicklin, S., Bruce, N.C. Appl. Environ. Microbiol. (1995) [Pubmed]
  5. Shewanella sediminis sp. nov., a novel Na+-requiring and hexahydro-1,3,5-trinitro-1,3,5-triazine-degrading bacterium from marine sediment. Zhao, J.S., Manno, D., Beaulieu, C., Paquet, L., Hawari, J. Int. J. Syst. Evol. Microbiol. (2005) [Pubmed]
  6. Spin trapping of nitrogen dioxide radical from photolytic decomposition of nitramines. Pace, M.D., Kalyanaraman, B. Free Radic. Biol. Med. (1993) [Pubmed]
  7. Biotransformation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) by a rabbit liver cytochrome P450: insight into the mechanism of RDX biodegradation by Rhodococcus sp. strain DN22. Bhushan, B., Trott, S., Spain, J.C., Halasz, A., Paquet, L., Hawari, J. Appl. Environ. Microbiol. (2003) [Pubmed]
  8. Cloning, sequencing, and characterization of the hexahydro-1,3,5-Trinitro-1,3,5-triazine degradation gene cluster from Rhodococcus rhodochrous. Seth-Smith, H.M., Rosser, S.J., Basran, A., Travis, E.R., Dabbs, E.R., Nicklin, S., Bruce, N.C. Appl. Environ. Microbiol. (2002) [Pubmed]
  9. Gene expression changes in Arabidopsis thaliana seedling roots exposed to the munition hexahydro-1,3,5-trinitro-1,3,5-triazine. Ekman, D.R., Wolfe, N.L., Dean, J.F. Environ. Sci. Technol. (2005) [Pubmed]
  10. Toxicity of the explosives 2,4,6-trinitrotoluene, hexahydro-1,3,5-trinitro-1,3,5-triazine, and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine in sediments to Chironomus tentans and Hyalella azteca: low-dose hormesis and high-dose mortality. Steevens, J.A., Duke, B.M., Lotufo, G.R., Bridges, T.S. Environ. Toxicol. Chem. (2002) [Pubmed]
  11. Metabolism of explosive compounds by sulfate-reducing bacteria. Boopathy, R., Gurgas, M., Ullian, J., Manning, J.F. Curr. Microbiol. (1998) [Pubmed]
  12. Toxicology of cyclotrimethylenetrinitramine: distribution and metabolism in the rat and the miniature swine. Schneider, N.R., Bradley, S.L., Andersen, M.E. Toxicol. Appl. Pharmacol. (1977) [Pubmed]
  13. Hexahydro-1,3,5-trinitro-1,3,5-triazine transformation by biologically reduced ferrihydrite: evolution of Fe mineralogy, surface area, and reaction rates. Williams, A.G., Gregory, K.B., Parkin, G.F., Scherer, M.M. Environ. Sci. Technol. (2005) [Pubmed]
  14. Theoretical predictions of chemical degradation reaction mechanisms of RDX and other cyclic nitramines derived from their molecular structures. Qasim, M., Fredrickson, H., McGrath, C., Furey, J., Bajpai, R. SAR and QSAR in environmental research. (2005) [Pubmed]
  15. Liquid chromatography/mass spectrometric analysis of explosives: RDX adduct ions. Gapeev, A., Sigman, M., Yinon, J. Rapid Commun. Mass Spectrom. (2003) [Pubmed]
  16. Bioavailability of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) to the prairie vole (Microtus ochrogaster). Fellows, R.J., Driver, C.R., Cataldo, D.A., Harvey, S.D. Environ. Toxicol. Chem. (2006) [Pubmed]
  17. N-Nitroso compounds produced in deer mouse (Peromyscus maniculatus) GI tracts following hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) exposure. Pan, X., Zhang, B., Smith, J.N., Francisco, M.S., Anderson, T.A., Cobb, G.P. Chemosphere (2007) [Pubmed]
  18. Abiotic transformation of hexahydro-1,3,5-trinitro-1,3,5-triazine by Fe(II) bound to magnetite. Gregory, K.B., Larese-Casanova, P., Parkin, G.F., Scherer, M.M. Environ. Sci. Technol. (2004) [Pubmed]
  19. Shewanella halifaxensis sp. nov., a novel obligately respiratory and denitrifying psychrophile. Zhao, J.S., Manno, D., Leggiadro, C., O'Neil, D., Hawari, J. Int. J. Syst. Evol. Microbiol. (2006) [Pubmed]
  20. Single-sided membrane introduction mass spectrometry for on-line determination of semi-volatile organic compounds in air. Riter, L.S., Takáts, Z., Cooks, R.G. The Analyst. (2001) [Pubmed]
  21. Dissolution rates of three high explosive compounds: TNT, RDX, and HMX. Lynch, J.C., Brannon, J.M., Delfino, J.J. Chemosphere (2002) [Pubmed]
  22. Acute and chronic toxicity of the new explosive CL-20 to the earthworm (Eisenia andrei) exposed to amended natural soils. Robidoux, P.Y., Sunahara, G.I., Savard, K., Berthelot, Y., Dodard, S., Martel, M., Gong, P., Hawari, J. Environ. Toxicol. Chem. (2004) [Pubmed]
  23. Dissolution of composition B detonation residuals. Lever, J.H., Taylor, S., Perovich, L., Bjella, K., Packer, B. Environ. Sci. Technol. (2005) [Pubmed]
  24. Acute hexogen poisoning after occupational exposure. Testud, F., Glanclaude, J.M., Descotes, J. J. Toxicol. Clin. Toxicol. (1996) [Pubmed]
  25. Trace level analysis of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and its biodegradation intermediates in liquid media by solid-phase extraction and high-pressure liquid chromatography analysis. Chow, T.M., Wilcoxon, M.R., Piwoni, M.D., Adrian, N.R. Journal of chromatographic science. (2004) [Pubmed]
  26. Use of pressurized liquid extraction (PLE)/gas chromatography-electron capture detection (GC-ECD) for the determination of biodegradation intermediates of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in soils. Zhang, B., Pan, X., Cobb, G.P., Anderson, T.A. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2005) [Pubmed]
  27. The responses of selected terrestrial plants to short (<12 days) and long term (2, 4 and 6 weeks) hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) exposure. Part I: Growth and developmental effects. Winfield, L.E., Rodgers, J.H., D'Surney, S.J. Ecotoxicology (2004) [Pubmed]
  28. Epidemiology, clinical features and treatment of idiopathic retroperitoneal fibrosis: our experience. Tralce, L., Antonelli, A., Dotti, P., Cunico, S.C. Archivio italiano di urologia, andrologia : organo ufficiale [di] Società italiana di ecografia urologica e nefrologica / Associazione ricerche in urologia. (2004) [Pubmed]
  29. Comparison of transcriptional responses in liver tissue and primary hepatocyte cell cultures after exposure to hexahydro-1, 3, 5-trinitro-1, 3, 5-triazine. Perkins, E.J., Bao, W., Guan, X., Ang, C.Y., Wolfinger, R.D., Chu, T.M., Meyer, S.A., Inouye, L.S. BMC Bioinformatics (2006) [Pubmed]
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