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Chemical Compound Review

ADTA     1,3,4-thiadiazol-2-amine

Synonyms: ATDA, A-TDA, PubChem8411, SureCN26211, NSC-4728, ...
 
 
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Disease relevance of Aminothiadiazole

 

High impact information on Aminothiadiazole

 

Chemical compound and disease context of Aminothiadiazole

 

Anatomical context of Aminothiadiazole

 

Analytical, diagnostic and therapeutic context of Aminothiadiazole

References

  1. Effects of 2-amino-1,3,4-thiadiazole on ribonucleotide pools of leukemia L1210 cells. Nelson, J.A., Rose, L.M., Bennett, L.L. Cancer Res. (1976) [Pubmed]
  2. High-dose aminothiadiazole in advanced colorectal cancer. An Illinois Cancer Center phase II trial. Locker, G.Y., Kilton, L., Khandekar, J.D., Lad, T.E., Knop, R.H., Albain, K., Blough, R., French, S., Benson, A.B. Investigational new drugs. (1994) [Pubmed]
  3. Phase II trials of 5-day vinblastine infusion (NSC 49842), L-alanosine (NSC 153353), acivicin (NSC 163501), and aminothiadiazole (NSC 4728) in patients with recurrent or metastatic renal cell carcinoma. Elson, P.J., Kvols, L.K., Vogl, S.E., Glover, D.J., Hahn, R.G., Trump, D.L., Carbone, P.P., Earle, J.D., Davis, T.E. Investigational new drugs. (1988) [Pubmed]
  4. Aminothiadiazole (NSC 4728) in patients with advanced ovarian carcinoma. A phase II study of the Gynecologic Oncology Group. Asbury, R.F., Wilson, J., Blessing, J.A., Buchsbaum, H.J., DiSaia, P.J. Am. J. Clin. Oncol. (1986) [Pubmed]
  5. Mechanism of action of 2-amino-1,3,4-thiadiazole (NSC 4728). Nelson, J.A., Rose, L.M., Bennett, L.L. Cancer Res. (1977) [Pubmed]
  6. Studies of 7 beta-[2-(aminoaryl)acetamido]-cephalosporin derivatives. III. Synthesis and structure-activity relationships in the aminothiadiazole series. Goto, J., Sakane, K., Teraji, T. J. Antibiot. (1984) [Pubmed]
  7. The effect of aminothiadiazole on glycogenesis and glycogenolysis in fetal and neonatal rat liver. Beaudoin, A.R. Teratology (1983) [Pubmed]
  8. Aminothiadiazole (NSC 4728) in patients with advanced carcinoma of the endometrium. A phase II study of the Gynecologic Oncology group. Asbury, R.F., Blessing, J.A., McGuire, W.P., Hanjani, P., Mortel, R. Am. J. Clin. Oncol. (1990) [Pubmed]
  9. A phase II trail of aminothiadiazole in patients with mixed mesodermal tumors of the uterine corpus: a Gynecologic Oncology Group study. Asbury, R., Blessing, J.A., Moore, D. Am. J. Clin. Oncol. (1996) [Pubmed]
  10. Phase II study of aminothiadiazole in advanced squamous cell carcinoma of the esophagus. Engstrom, P.F., Ryan, L.M., Falkson, G., Haller, D.G. Am. J. Clin. Oncol. (1991) [Pubmed]
  11. Aminothiadiazole (NSC 4728) in patients with advanced nonsquamous carcinoma of the cervix. A phase II study of the Gynecologic Oncology Group. Asbury, R.F., Blessing, J.A., DiSaia, P.J., Malfetano, J. Am. J. Clin. Oncol. (1989) [Pubmed]
 
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