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Chemical Compound Review

Cardene     2-(benzyl-methyl-amino)ethyl methyl 2,6...

Synonyms: Nicardil, Bionicard, Nerdipine, Perdipine, Lincil, ...
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Disease relevance of nicardipine

  • Furthermore, MRI can be used in the diagnosis of anterior horn infection and would play an important role in diagnosis of poliomyelitis [Kornreich L, Dagan O, Grunebaum M. MRI in acute poliomyelitis. Neuroradiology 1996;38(4):371-2] [1].
  • A total of 112 infants were assigned into high-risk or low-risk group for serious bacterial infection by the application of the criteria proposed by Dagan et al. in 1985 [2].
 

High impact information on nicardipine

  • Sonicated phosphatidylserine:phosphatidylcholine:cholesterol liposomes were used as carriers of ADM, based on previous studies on the drug entrapment, stability, and tissue distribution of ADM-containing liposomes of various compositions (A. Gabizon, A. Dagan, D. Goren, Y. Barenholz, and Z. Fuks. Cancer Res., 42: 4734-4739, 1982) [3].
  • We have previously shown that cell surface proteoglycans protect the cell membrane from the action of extracellular phospholipase A2 (PLA2) enzymes [Dan, P., Nitzan, D. W., Dagan, A., Ginsburg, I., and Yedgar, S. (1996) FEBS Lett. 383, 75-78] [4].
  • Aplysia neurons grown in primary cell culture (Dagan and Levitan, 1981) were exposed to the putative neurotransmitters acetylcholine and serotonin by local iontophoretic application, and changes in membrane potential or voltage clamp currents were examined [5].
  • Three hundred 7-week-old Beit Dagan female mice underwent right nephrectomy or sham operation, and either remained virgin or were exposed to six repetitive pregnancies [6].
  • METHODS: Cell-attached and cell-free excised patches were formed from the basolateral membranes of NPE and single channel currents recorded with a Dagan 3900A patch clamp amplifier [7].
 

Biological context of nicardipine

 

Associations of nicardipine with other chemical compounds

References

  1. Clinical presentations of acute paralytic poliomyelitis. Arya, S.C., Agarwal, N. Vaccine (2006) [Pubmed]
  2. Fever in infants less than 3 months of age. Chiu, C.H., Lin, T.Y. Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui (1994) [Pubmed]
  3. Enhancement of adriamycin delivery to liver metastatic cells with increased tumoricidal effect using liposomes as drug carriers. Gabizon, A., Goren, D., Fuks, Z., Barenholz, Y., Dagan, A., Meshorer, A. Cancer Res. (1983) [Pubmed]
  4. Inhibition of type I and type II phospholipase A2 by phosphatidyl-ethanolamine linked to polymeric carriers. Dan, P., Dagan, A., Krimsky, M., Pruzanski, W., Vadas, P., Yedgar, S. Biochemistry (1998) [Pubmed]
  5. Sensitivity of Aplysia neurons in primary culture to putative neurotransmitters. Bodmer, R., Levitan, I.B. J. Neurobiol. (1984) [Pubmed]
  6. Uninephrectomy and repetitive pregnancies in mice: a combined stimulus for renal hypertrophy. Modai, D., Averbukh, Z., Weissgarten, J., Bogin, E., Rosenmann, E., Cohn, M., Goren, E., Shaked, U. Nephrol. Dial. Transplant. (1989) [Pubmed]
  7. A low conductance chloride channel in the basolateral membranes of the non-pigmented ciliary epithelium of the rabbit eye. Chen, S., Sears, M. Curr. Eye Res. (1997) [Pubmed]
  8. Bioequivalence of two orally administered nicardipine products. Buice, R.G., Subramanian, V., Lane, E. Biopharmaceutics & drug disposition. (1996) [Pubmed]
  9. Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 2: Effect on myocardial metabolism. Saitoh, C., Momose, K., Tanaka, H., Sato, S., Taguchi, K., Saitoh, M., Maehara, J., Asano, M., Usuda, S. Arzneimittel-Forschung. (1998) [Pubmed]
 
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