Chemical Compound Review:
PMEApp [[2-(6-aminopurin-9- yl)ethoxymethyl...
Synonyms:
PMEA-DP, PMEA-pp, CHEMBL1162433, CHEBI:42212, AC1L9LBO, ...
- Inhibition of reverse transcriptase from feline immunodeficiency virus by analogs of 2'-deoxyadenosine-5'-triphosphate. Cronn, R.C., Remington, K.M., Preston, B.D., North, T.W. Biochem. Pharmacol. (1992)
- Phosphonylmethyl ethers of acyclic nucleoside analogues: inhibitors of HSV-1 induced ribonucleotide reductase. Cerný, J., Votruba, I., Vonka, V., Rosenberg, I., Otmar, M., Holý, A. Antiviral Res. (1990)
- Biochemical pharmacology of acyclic nucleotide analogues. Bronson, J.J., Ho, H.T., De Boeck, H., Woods, K., Ghazzouli, I., Martin, J.C., Hitchcock, M.J. Ann. N. Y. Acad. Sci. (1990)
- In vitro characterization of the anti-human cytomegalovirus activity of PMEA (Adefovir). Xiong, X., Flores, C., Fuller, M.D., Mendel, D.B., Mulato, A.S., Moon, K., Chen, M.S., Cherrington, J.M. Antiviral Res. (1997)
- Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Shen, Y., Zhukovskaya, N.L., Zimmer, M.I., Soelaiman, S., Bergson, P., Wang, C.R., Gibbs, C.S., Tang, W.J. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound. Balzarini, J., Hao, Z., Herdewijn, P., Johns, D.G., De Clercq, E. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Herpes simplex virus-specified DNA polymerase is the target for the antiviral action of 9-(2-phosphonylmethoxyethyl)adenine. Foster, S.A., Cerny, J., Cheng, Y.C. J. Biol. Chem. (1991)
- Intracellular metabolism and action of acyclic nucleoside phosphonates on DNA replication. Pisarev, V.M., Lee, S.H., Connelly, M.C., Fridland, A. Mol. Pharmacol. (1997)
- Inhibition of human telomerase by diphosphates of acyclic nucleoside phosphonates. Hájek, M., Matulová, N., Votruba, I., Holý, A., Tloust'ová, E. Biochem. Pharmacol. (2005)
- Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro. Holý, A., Votruba, I., Merta, A., Cerný, J., Veselý, J., Vlach, J., Sedivá, K., Rosenberg, I., Otmar, M., Hrebabecký, H. Antiviral Res. (1990)
- 9-[2-(Phosphonomethoxy)ethyl]adenine diphosphate (PMEApp) as a substrate toward replicative DNA polymerases alpha, delta, epsilon, and epsilon*. Birkus, G., Votruba, I., Holý, A., Otová, B. Biochem. Pharmacol. (1999)