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Chemical Compound Review

PREGNANETRIOL     17-(1-hydroxyethyl)-10,13- dimethyl-1,2,3,4...

Synonyms: AC1LAPNB, AGN-PC-00HYNI, CTK8I2878, 520-86-5, MCULE-9460640127, ...
 
 
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Disease relevance of PREGNANETRIOL

 

High impact information on PREGNANETRIOL

 

Chemical compound and disease context of PREGNANETRIOL

 

Biological context of PREGNANETRIOL

  • Using this method in 7 healthy women (aged 28-37) with normal menstrual cycles the urinary excretion of alpha- and beta-pregnanediol and pregnanetriol were evaluated every second day (starting the 6th day of the cycle) [12].
  • As the 17-hydroxy-pregnanolone is demonstrable after mild acid hydrolysis, too, it can be applied independently from the pregnanetriol determination [4].
 

Anatomical context of PREGNANETRIOL

 

Associations of PREGNANETRIOL with other chemical compounds

 

Analytical, diagnostic and therapeutic context of PREGNANETRIOL

References

  1. Management of congenital adrenal hyperplasia using serum dehydroepiandrosterone sulfate and 17-hydroxyprogesterone concentrations. Golden, M.P., Lippe, B.M., Kaplan, S.A., Lavin, N., Slavin, J. Pediatrics (1978) [Pubmed]
  2. Urinary pregnanetriol excretion in hirsutism. Van't Hoff, W., Bicknell, E.J., Horrocks, P.M., Fleetwood, J.A., Inthuprapa, M., Hall, R. Clin. Chim. Acta (1977) [Pubmed]
  3. The urinary excretion of pregnanetriol and pregnenetriol in patients with breast cancer. A postulation on the meaning of Bulbrook's discriminant. Gonçalves Sobrinho, L., Faro, L., Henriques, E.F., Botelho, L.S., Fontes De Sousa, M.F. European journal of cancer. (1976) [Pubmed]
  4. Significance of 3alpha, 17 alpha-dihydroxy-5beta-pregnane-20-one in the diagnosis of congenital adrenal hyperplasia. Kecskés, L., Tényi, I., Németh, M., Juricskay, Z., Temesi, M. Endokrinologie. (1975) [Pubmed]
  5. Management of virilizing congenital adrenal hyperplasia with cyproheptadine. Hsu, T.H. Ann. Intern. Med. (1980) [Pubmed]
  6. Angiotensin and adrenal steroidogenesis: study of 21-hydroxylase-deficient congenital adrenal hyperplasia. Schaison, G., Couzinet, B., Gourmelen, M., Elkik, F., Bougneres, P. J. Clin. Endocrinol. Metab. (1980) [Pubmed]
  7. Isolation of urinary C-20 alpha- and C-20 beta-hydroxy-C21-steroid metabolites in cases of congenital adrenal hyperplasia, postpubertal virilizing syndrome and polycystic ovary syndrome. Halperin, G., Maschler, I. Steroids (1979) [Pubmed]
  8. Tamoxifen-induced nonalcoholic steatohepatitis in breast cancer patients treated with adjuvant tamoxifen. Nemoto, Y., Saibara, T., Ogawa, Y., Zhang, T., Xu, N., Ono, M., Akisawa, N., Iwasaki, S., Maeda, T., Onishi, S. Intern. Med. (2002) [Pubmed]
  9. Dissociation of plasma renin activity and plasma aldosterone level during dexamethasone suppression test in non-salt-losers with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Kinoshita, K., Ishida, H., Minowada, S., Niijima, T. Endocrinol. Jpn. (1980) [Pubmed]
  10. Urinary pregnanetriol and delta 5-pregnentriol in women with idiopathic hirsutism. Pal, S.B. Endokrinologie. (1979) [Pubmed]
  11. Increased urinary excretion of total 16 alpha-hydroxypregnenolone in newborn infants with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Homoki, J., Teller, W.M. Klin. Wochenschr. (1982) [Pubmed]
  12. A modification of the Detter and Klingmüller's method for urinary alpha- and beta-pregnanediol and pregnanetriol determination: excretion patterns in men and in women during the normal menstrual cycle. Buntner, B., Sliwiński, A. Endokrinologie. (1975) [Pubmed]
  13. X-linked congenital adrenal hypoplasia: proposal pathogenesis. Preeyasombat, C., Sriphrapradang, A., Chaubtam, L. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. (1989) [Pubmed]
  14. Congenital adrenal hyperplasia due to deficient cholesterol side-chain cleavage activity (20, 22-desmolase) in a patient treated for 18 years. Hauffa, B.P., Miller, W.L., Grumbach, M.M., Conte, F.A., Kaplan, S.L. Clin. Endocrinol. (Oxf) (1985) [Pubmed]
  15. A possible defect in the inter-conversion between cortisone and cortisol in prepubertal patients with congenital adrenal hyperplasia receiving cortisone acetate therapy. Whorwood, C.B., Warne, G.L. J. Steroid Biochem. Mol. Biol. (1991) [Pubmed]
  16. Non-invasive monitoring of ovarian function in Asian elephants (Elephas maximus) by measurement of urinary 5 beta-pregnanetriol. Niemuller, C.A., Shaw, H.J., Hodges, J.K. J. Reprod. Fertil. (1993) [Pubmed]
  17. Partial 11- and 21-hydroylase deficiencies in hirsute women. Newmark, S., Dluhy, R.G., Williams, G.H., Pochi, P., Rose, L.I. Am. J. Obstet. Gynecol. (1977) [Pubmed]
  18. Improved method for the measurement of pregnanetriol in urine. Hammond, J.E., Phillips, J.C., Savory, J. Ann. Clin. Lab. Sci. (1979) [Pubmed]
  19. The radioimmunoassay of pregnanetriol 3 alpha-glucuronide. Samarajeewa, P., Kellie, A.E. J. Steroid Biochem. (1985) [Pubmed]
 
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