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Chemical Compound Review

MK-476     sodium 2-[1-[[(1R)-1-[3-[(E)-2-(7...

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Disease relevance of montelukast


High impact information on montelukast


  1. Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile. Balani, S.K., Xu, X., Pratha, V., Koss, M.A., Amin, R.D., Dufresne, C., Miller, R.R., Arison, B.H., Doss, G.A., Chiba, M., Freeman, A., Holland, S.D., Schwartz, J.I., Lasseter, K.C., Gertz, B.J., Isenberg, J.I., Rogers, J.D., Lin, J.H., Baillie, T.A. Drug Metab. Dispos. (1997) [Pubmed]
  2. Antileukotriene treatment and allergic rhinitis-related cough in guinea pigs. Brozmanova, M., Plevkova, J., Bartos, V., Plank, L., Tatar, M. J. Physiol. Pharmacol. (2005) [Pubmed]
  3. The effect of montelukast on exhaled nitric oxide and lung function in asthmatic children 2 to 5 years old. Straub, D.A., Minocchieri, S., Moeller, A., Hamacher, J., Wildhaber, J.H. Chest (2005) [Pubmed]
  4. Pharmacokinetics, bioavailability, and safety of montelukast sodium (MK-0476) in healthy males and females. Cheng, H., Leff, J.A., Amin, R., Gertz, B.J., De Smet, M., Noonan, N., Rogers, J.D., Malbecq, W., Meisner, D., Somers, G. Pharm. Res. (1996) [Pubmed]
  5. A series of non-quinoline cysLT1 receptor antagonists: SAR study on pyridyl analogs of Singulair. Guay, D., Gauthier, J.Y., Dufresne, C., Jones, T.R., McAuliffe, M., McFarlane, C., Metters, K.M., Prasit, P., Rochette, C., Roy, P., Sawyer, N., Zamboni, R. Bioorg. Med. Chem. Lett. (1998) [Pubmed]
  6. A novel photoaffinity probe for the LTD4 receptor. Gallant, M., Sawyer, N., Metters, K.M., Zamboni, R.J. Bioorg. Med. Chem. (1998) [Pubmed]
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