The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

AC1NSMED     3-[2-[4-(4- fluorophenyl)carbonyl-1...

Synonyms: MOLI000115, MOLI001676, [18F]Altanserin
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Psychiatry related information on MOLI001676

  • RESULTS: No significant abnormalities in [18F]altanserin binding (binding potential) were observed in the patients with late-life depression, and no effect of depression on binding potential was present within the Alzheimer's disease group [1].

High impact information on MOLI001676


Biological context of MOLI001676


Anatomical context of MOLI001676


Associations of MOLI001676 with other chemical compounds


Analytical, diagnostic and therapeutic context of MOLI001676


  1. PET imaging of serotonin type 2A receptors in late-life neuropsychiatric disorders. Meltzer, C.C., Price, J.C., Mathis, C.A., Greer, P.J., Cantwell, M.N., Houck, P.R., Mulsant, B.H., Ben-Eliezer, D., Lopresti, B., DeKosky, S.T., Reynolds, C.F. The American journal of psychiatry. (1999) [Pubmed]
  2. [18F]altanserin binding to human 5HT2A receptors is unaltered after citalopram and pindolol challenge. Pinborg, L.H., Adams, K.H., Yndgaard, S., Hasselbalch, S.G., Holm, S., Kristiansen, H., Paulson, O.B., Knudsen, G.M. J. Cereb. Blood Flow Metab. (2004) [Pubmed]
  3. Decreased hippocampal 5-HT2A receptor binding in major depressive disorder: in vivo measurement with [18F]altanserin positron emission tomography. Mintun, M.A., Sheline, Y.I., Moerlein, S.M., Vlassenko, A.G., Huang, Y., Snyder, A.Z. Biol. Psychiatry (2004) [Pubmed]
  4. Reduced 5-HT2A receptor binding after recovery from anorexia nervosa. Frank, G.K., Kaye, W.H., Meltzer, C.C., Price, J.C., Greer, P., McConaha, C., Skovira, K. Biol. Psychiatry (2002) [Pubmed]
  5. Reduced binding of [18F]altanserin to serotonin type 2A receptors in aging: persistence of effect after partial volume correction. Meltzer, C.C., Smith, G., Price, J.C., Reynolds, C.F., Mathis, C.A., Greer, P., Lopresti, B., Mintun, M.A., Pollock, B.G., Ben-Eliezer, D., Cantwell, M.N., Kaye, W., DeKosky, S.T. Brain Res. (1998) [Pubmed]
  6. Characterization of radioactive metabolites of 5-HT2A receptor PET ligand [18F]altanserin in human and rodent. Tan, P.Z., Baldwin, R.M., Van Dyck, C.H., Al-Tikriti, M., Roth, B., Khan, N., Charney, D.S., Innis, R.B. Nucl. Med. Biol. (1999) [Pubmed]
  7. Test-retest variability of serotonin 5-HT2A receptor binding measured with positron emission tomography and [18F]altanserin in the human brain. Smith, G.S., Price, J.C., Lopresti, B.J., Huang, Y., Simpson, N., Holt, D., Mason, N.S., Meltzer, C.C., Sweet, R.A., Nichols, T., Sashin, D., Mathis, C.A. Synapse (1998) [Pubmed]
  8. The hippocampus and depression. Sheline, Y.I., Mittler, B.L., Mintun, M.A. Eur. Psychiatry (2002) [Pubmed]
  9. Visualisation of loss of 5-HT2A receptors with age in healthy volunteers using [18F]altanserin and positron emission tomographic imaging. Rosier, A., Dupont, P., Peuskens, J., Bormans, G., Vandenberghe, R., Maes, M., de Groot, T., Schiepers, C., Verbruggen, A., Mortelmans, L. Psychiatry research. (1996) [Pubmed]
  10. Serotonin 5HT2 receptor imaging in the human brain using positron emission tomography and a new radioligand, [18F]altanserin: results in young normal controls. Sadzot, B., Lemaire, C., Maquet, P., Salmon, E., Plenevaux, A., Degueldre, C., Hermanne, J.P., Guillaume, M., Cantineau, R., Comar, D. J. Cereb. Blood Flow Metab. (1995) [Pubmed]
  11. Fluorine-18-altanserin: a radioligand for the study of serotonin receptors with PET: radiolabeling and in vivo biologic behavior in rats. Lemaire, C., Cantineau, R., Guillaume, M., Plenevaux, A., Christiaens, L. J. Nucl. Med. (1991) [Pubmed]
  12. Multicompartmental study of fluorine-18 altanserin binding to brain 5HT2 receptors in humans using positron emission tomography. Biver, F., Goldman, S., Luxen, A., Monclus, M., Forestini, M., Mendlewicz, J., Lotstra, F. European journal of nuclear medicine. (1994) [Pubmed]
WikiGenes - Universities