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Chemical Compound Review

AC1Q6CQH     8-[4-oxo-5-[(E)-pent-2-enyl]- 1-cyclopent-2...

Synonyms: AR-1E1004, LS-186742, LS-187429, AC1O27PP, 12-Oxo-pda, ...
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High impact information on 12-Oxo-phytodienoic acid


Associations of 12-Oxo-phytodienoic acid with other chemical compounds

  • This and further data indicate that endogenous synthesis of the JA precursor 12-oxophytodienoic acid, as well as of JA and its methyl ester, are not induced in tomato leaves, suggesting that positive feedback in JA biosynthesis does not function in vivo [6].

Gene context of 12-Oxo-phytodienoic acid


Analytical, diagnostic and therapeutic context of 12-Oxo-phytodienoic acid

  • Experiments with synthetic trihomojasmonate demonstrated that beta-oxidation is not a prerequisite for biological activity and that 12-oxophytodienoic acid and derivatives are most likely fully active as signal transducers [9].


  1. A novel class of oxylipins, sn1-O-(12-oxophytodienoyl)-sn2-O-(hexadecatrienoyl)-monogalactosyl Diglyceride, from Arabidopsis thaliana. Stelmach, B.A., Müller, A., Hennig, P., Gebhardt, S., Schubert-Zsilavecz, M., Weiler, E.W. J. Biol. Chem. (2001) [Pubmed]
  2. A homolog of old yellow enzyme in tomato. Spectral properties and substrate specificity of the recombinant protein. Strassner, J., Fürholz, A., Macheroux, P., Amrhein, N., Schaller, A. J. Biol. Chem. (1999) [Pubmed]
  3. The role of EDS1 (enhanced disease susceptibility) during singlet oxygen-mediated stress responses of Arabidopsis. Ochsenbein, C., Przybyla, D., Danon, A., Landgraf, F., Göbel, C., Imboden, A., Feussner, I., Apel, K. Plant J. (2006) [Pubmed]
  4. Ion channel-forming alamethicin is a potent elicitor of volatile biosynthesis and tendril coiling. Cross talk between jasmonate and salicylate signaling in lima bean. Engelberth, J., Koch, T., Schüler, G., Bachmann, N., Rechtenbach, J., Boland, W. Plant Physiol. (2001) [Pubmed]
  5. Cloning and characterization of a jasmonic acid-responsive gene encoding 12-oxophytodienoic acid reductase in suspension-cultured rice cells. Sobajima, H., Takeda, M., Sugimori, M., Kobashi, N., Kiribuchi, K., Cho, E.M., Akimoto, C., Yamaguchi, T., Minami, E., Shibuya, N., Schaller, F., Weiler, E.W., Yoshihara, T., Nishida, H., Nojiri, H., Omori, T., Nishiyama, M., Yamane, H. Planta (2003) [Pubmed]
  6. Octadecanoid and jasmonate signaling in tomato (Lycopersicon esculentum Mill.) leaves: endogenous jasmonates do not induce jasmonate biosynthesis. Miersch, O., Wasternack, C. Biol. Chem. (2000) [Pubmed]
  7. Structure and regulation of OPR1 and OPR2, two closely related genes encoding 12-oxophytodienoic acid-10,11-reductases from Arabidopsis thaliana. Biesgen, C., Weiler, E.W. Planta (1999) [Pubmed]
  8. Jasmonate is involved in the induction of tyrosine aminotransferase and tocopherol biosynthesis in Arabidopsis thaliana. Sandorf, I., Holländer-Czytko, H. Planta (2002) [Pubmed]
  9. The octadecanoic pathway: signal molecules for the regulation of secondary pathways. Blechert, S., Brodschelm, W., Hölder, S., Kammerer, L., Kutchan, T.M., Mueller, M.J., Xia, Z.Q., Zenk, M.H. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
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