Disease relevance of Cab39

• In this study, we sought to determine whether the 39kDa HagB protein could be stably expressed on the surface of an avirulent Salmonella vaccine strain [1].
• The role of a 39kDa protein of avian Pasteurella multocida in pathogenesis of fowl cholera was investigated using monoclonal antibodies (Mabs) [2].
• Purification and characterization of a 39kDa apurinic/apyrimidinic endonuclease from mouse ascites sarcoma cells [3].

High impact information on Cab39

• Mammalian DNA polymerase beta(beta-pol) is a single polypeptide chain enzyme of 39kDa. beta-pol has enzymatic activities appropriate for roles in base excision repair and other DNA metabolism events involving gap-filling DNA synthesis [4].
• The predicted amino acid sequence revealed that the MO25 gene may encode a Ca2+ binding protein [5].
• The unidentified sequence (MO25) was found at low levels in the unfertilized egg, but increased at the 2-cell stage [5].
• Immunoblot analysis of the hybridomas revealed that all the Mabs recognized a 39kDa protein of CCE [2].

Analytical, diagnostic and therapeutic context of Cab39

• Western blotting analysis demonstrated that two proteins of a Mr of 39kDa and 22kDa were the main targets for the Mabs [6].

References