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Gene Review

CYLC1  -  cylicin, basic protein of sperm head...

Homo sapiens

Synonyms: CYL, CYL1, Cylicin I, Cylicin-1, Multiple-band polypeptide I
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Disease relevance of CYLC1


High impact information on CYLC1


Anatomical context of CYLC1

  • As with cylicin I mRNA, the 2.6-kb mRNA has also been shown to be specifically expressed in testis [3].

Analytical, diagnostic and therapeutic context of CYLC1

  • The use of Histolyn CYL in an enzyme immunoassay to detect Histoplasma capsulatum antibodies [5].
  • Minimal cross reactivity was evidenced when Histolyn CYL was used in the ELISA to detect anti-Coccidioides immitis antibody in sera from infected animals and humans [5].


  1. Histoplasmin-CYL, a yeast phase reagent in skin test studies with humans. Levine, H.B., Scalarone, G.M., Campbell, G.D., Graybill, J.R., Kelly, P.C., Chaparas, S.D. Am. Rev. Respir. Dis. (1979) [Pubmed]
  2. Molecular characterization of mammalian cylicin, a basic protein of the sperm head cytoskeleton. Hess, H., Heid, H., Franke, W.W. J. Cell Biol. (1993) [Pubmed]
  3. The protein complexity of the cytoskeleton of bovine and human sperm heads: the identification and characterization of cylicin II. Hess, H., Heid, H., Zimbelmann, R., Franke, W.W. Exp. Cell Res. (1995) [Pubmed]
  4. The cytoskeleton of mammalian spermatozoa. Fouquet, J.P., Kann, M.L. Biol. Cell (1994) [Pubmed]
  5. The use of Histolyn CYL in an enzyme immunoassay to detect Histoplasma capsulatum antibodies. Boyer, M.J., Scalarone, G.M. Sabouraudia. (1983) [Pubmed]
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