Gene Review:
Mnt - max binding protein
Mus musculus
Synonyms:
Max-binding protein MNT, Myc antagonist MNT, Protein ROX, Rox, bHLHd3
- Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites. Hurlin, P.J., Quéva, C., Eisenman, R.N. Genes Dev. (1997)
- Inflammatory disease and lymphomagenesis caused by deletion of the Myc antagonist Mnt in T cells. Dezfouli, S., Bakke, A., Huang, J., Wynshaw-Boris, A., Hurlin, P.J. Mol. Cell. Biol. (2006)
- Mnt: a novel Max-interacting protein and Myc antagonist. Hurlin, P.J., Qúeva, C., Eisenman, R.N. Curr. Top. Microbiol. Immunol. (1997)
- Mnt-Max to Myc-Max complex switching regulates cell cycle entry. Walker, W., Zhou, Z.Q., Ota, S., Wynshaw-Boris, A., Hurlin, P.J. J. Cell Biol. (2005)
- Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis. Hurlin, P.J., Zhou, Z.Q., Toyo-oka, K., Ota, S., Walker, W.L., Hirotsune, S., Wynshaw-Boris, A. EMBO J. (2003)
- Genomic organization of the murine Miller-Dieker/lissencephaly region: conservation of linkage with the human region. Hirotsune, S., Pack, S.D., Chong, S.S., Robbins, C.M., Pavan, W.J., Ledbetter, D.H., Wynshaw-Boris, A. Genome Res. (1997)
- Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif. Hurlin, P.J., Steingrìmsson, E., Copeland, N.G., Jenkins, N.A., Eisenman, R.N. EMBO J. (1999)
- Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Toyo-oka, K., Bowen, T.J., Hirotsune, S., Li, Z., Jain, S., Ota, S., Escoubet-Lozach, L., Lozach, L.E., Garcia-Bassets, I., Bassett, I.G., Lozach, J., Rosenfeld, M.G., Glass, C.K., Eisenman, R., Ren, B., Hurlin, P., Wynshaw-Boris, A. Cancer Res. (2006)
- Mnt transcriptional repressor is functionally regulated during cell cycle progression. Popov, N., Wahlström, T., Hurlin, P.J., Henriksson, M. Oncogene (2005)
- Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation. Nilsson, J.A., Maclean, K.H., Keller, U.B., Pendeville, H., Baudino, T.A., Cleveland, J.L. Mol. Cell. Biol. (2004)
- Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor. Meroni, G., Reymond, A., Alcalay, M., Borsani, G., Tanigami, A., Tonlorenzi, R., Nigro, C.L., Messali, S., Zollo, M., Ledbetter, D.H., Brent, R., Ballabio, A., Carrozzo, R. EMBO J. (1997)