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Gene Review

klp-3  -  Protein KLP-3

Caenorhabditis elegans

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High impact information on klp-3


Biological context of klp-3

  • Similarly, expression of a klp-3 antisense RNA, under the control of a heat shock promoter, causes embryonic arrest, dead eggs and polyploid cells in transgenic lines, suggesting a critical role for the klp-3 function in chromosome segregation [1].

Analytical, diagnostic and therapeutic context of klp-3

  • Northern blot analysis using the klp-3 cDNA probe reveals a 1.9 kb mRNA that is transcribed at a low level during development [1].


  1. Molecular cloning and expression of the Caenorhabditis elegans klp-3, an ortholog of C terminus motor kinesins Kar3 and ncd. Khan, M.L., Gogonea, C.B., Siddiqui, Z.K., Ali, M.Y., Kikuno, R., Nishikawa, K., Siddiqui, S.S. J. Mol. Biol. (1997) [Pubmed]
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