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Gene Review

Slc26a1  -  solute carrier family 26 (sulfate...

Mus musculus

Synonyms: SAT-1, Sat1, Solute carrier family 26 member 1, Sulfate anion transporter 1
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Disease relevance of Slc26a1


High impact information on Slc26a1

  • Drugs found earlier to interact with sulfate transport in vivo have not yet been tested with sat-1 [2].
  • Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1 [3].
  • Functional comparison with murine Slc26a1, the basolateral oxalate exchanger of the proximal tubule, reveals a number of intriguing differences [3].
  • In contrast, SO and oxalate transport by Slc26a1 are mutually cis-inhibited but activated significantly by extracellular halides, lactate, and formate [3].
  • Also, the expression of mRNA for GlnT (SAT1), a system A isoform specific for Gln, was only expressed in neurons derived from both structures, while an alanine (Ala)-preferring system A transporter, SAT2, was expressed in neurons and astrocytes from either region [4].

Biological context of Slc26a1


Anatomical context of Slc26a1


Analytical, diagnostic and therapeutic context of Slc26a1


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