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Gene Review

mcm2  -  MCM complex subunit Mcm2

Schizosaccharomyces pombe 972h-

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High impact information on cdc19


Biological context of cdc19

  • We investigated the basis for this late S phase arrest by analyzing the effects of a temperature-sensitive mutation in fission yeast cdc19(+ )(mcm2(+)). cdc19-P1 cells show a dramatic loss of viability at the restrictive temperature, which is not typical of all S phase mutants [5].
  • The histidine-tagged nda1+ gene was constructed and integrated into the chromosome to replace the wild-type nda1+ gene [6].

Analytical, diagnostic and therapeutic context of cdc19


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