High impact information on CD9

• We further demonstrate that tetraspanins CD9, CD81, and CD82 can stabilize their partner protein CD4 [1].
• Expression of fertilin and CD9 in bovine trophoblast and endometrium during implantation [2].
• Immunoprecipitation followed by Western blot analysis showed association between CD9 and integrin alpha3 in endometrium [2].
• The results support the hypothesis that fertilin and CD9 are involved in bovine binucleate cell migration and fusion [2].
• Normal and transformed cell lines established from the ocular ciliary epithelium exhibited significant levels of CD9 transcripts [3].

Biological context of CD9

• The bovine CD9 clone contains an open reading frame of 226 amino acids (M(r) 24,860) [3].
• We have isolated a cDNA clone from a lambda gt11 cDNA library of bovine ocular ciliary epithelial cells encoding the CD9 antigen, a member of a new family of transmembrane proteins [3].

Anatomical context of CD9

• Analysis of bovine ocular tissues reveals that the CD9 gene encodes a 1.4 kb mRNA which is detectable predominantly in cornea and at low levels in ciliary epithelium, retina, iris, and lens [3].

Analytical, diagnostic and therapeutic context of CD9

• Molecular cloning of the bovine CD9 antigen from ocular ciliary epithelial cells [3].

References