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Gene Review

TTR  -  transthyretin

Bos taurus

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Disease relevance of TTR

  • The maximum TTR during prolonged hyperthermia at 41 degrees C was 2.4 by approximately 50 min [1].
  • The finding of TTR synthesis in the eye may explain ocular involvement in the familial amyloidotic polyneuropathies [2].
  • A prealbumin (electrophoretic mobility relative to albumin; Ra 1.28) and a pretransferrin (Ra .72) were found in uterine flushings [3].

High impact information on TTR


Anatomical context of TTR


Analytical, diagnostic and therapeutic context of TTR


  1. The thermal response and development of thermotolerance of the bone marrow stromal progenitor CFU-F. O'Hara, M.D., Lin, C., Leeper, D.B. Exp. Hematol. (1991) [Pubmed]
  2. Transthyretin is synthesized in the mammalian eye. Martone, R.L., Herbert, J., Dwork, A., Schon, E.A. Biochem. Biophys. Res. Commun. (1988) [Pubmed]
  3. Profiles of uterine protein in flushings and progesterone in plasma of normal and repeat-breeding dairy cattle. Guise, M.B., Gwazdauskas, F.C. J. Dairy Sci. (1987) [Pubmed]
  4. Retinol-binding protein is synthesized in the mammalian eye. Martone, R.L., Schon, E.A., Goodman, D.S., Soprano, D.R., Herbert, J. Biochem. Biophys. Res. Commun. (1988) [Pubmed]
  5. Plasma protein synthesis and serum amino acids in dry and lactating dairy cows. Pösö, A.R., Lindberg, L.A. Zentralblatt für Veterinärmedizin. Reihe A. (1994) [Pubmed]
  6. Purification of a bovine counterpart to human prealbumin and its interaction with a bovine retinol-binding protein. Fex, G., Lindgren, R. Biochim. Biophys. Acta (1977) [Pubmed]
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