Gene Review:
Orc1 - Origin recognition complex subunit 1
Drosophila melanogaster
Synonyms:
CG10667, DmORC1, DmOrc1, DmOrc1p, Dmel\CG10667, ...
- Drosophila ORC specifically binds to ACE3, an origin of DNA replication control element. Austin, R.J., Orr-Weaver, T.L., Bell, S.P. Genes Dev. (1999)
- DNA replication control through interaction of E2F-RB and the origin recognition complex. Bosco, G., Du, W., Orr-Weaver, T.L. Nat. Cell Biol. (2001)
- DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding. Remus, D., Beall, E.L., Botchan, M.R. EMBO J. (2004)
- Role of the Orc6 Protein in Origin Recognition Complex-Dependent DNA Binding and Replication in Drosophila melanogaster. Balasov, M., Huijbregts, R.P., Chesnokov, I. Mol. Cell. Biol. (2007)
- CDK phosphorylation inhibits the DNA-binding and ATP-hydrolysis activities of the Drosophila origin recognition complex. Remus, D., Blanchette, M., Rio, D.C., Botchan, M.R. J. Biol. Chem. (2005)
- Linking cell-cycle dysfunction in Alzheimer's disease to a failure of synaptic plasticity. Arendt, T., Brückner, M.K. Biochim. Biophys. Acta (2007)