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Gene Review

NEUROD2  -  neuronal differentiation 2

Homo sapiens

Synonyms: BHLHA1, Class A basic helix-loop-helix protein 1, NDRF, NeuroD-related factor, NeuroD2, ...
 
 
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Disease relevance of NEUROD2

  • In this paper, we show that transduction of NeuroD2 protein induced mouse neuroblastoma cell line N1E-115 into neural differentiation [1].
 

High impact information on NEUROD2

 

Biological context of NEUROD2

 

Anatomical context of NEUROD2

 

Analytical, diagnostic and therapeutic context of NEUROD2

References

  1. Transduction of NeuroD2 protein induced neural cell differentiation. Noda, T., Kawamura, R., Funabashi, H., Mie, M., Kobatake, E. J. Biotechnol. (2006) [Pubmed]
  2. The proneural genes NEUROD1 and NEUROD2 are expressed during human trophoblast invasion. Westerman, B.A., Poutsma, A., Maruyama, K., Schrijnemakers, H.F., van Wijk, I.J., Oudejans, C.B. Mech. Dev. (2002) [Pubmed]
  3. NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively. Tamimi, R.M., Steingrimsson, E., Montgomery-Dyer, K., Copeland, N.G., Jenkins, N.A., Tapscott, S.J. Genomics (1997) [Pubmed]
  4. Interaction of PKN with a neuron-specific basic helix-loop-helix transcription factor, NDRF/NeuroD2. Shibata, H., Oda, H., Mukai, H., Oishi, K., Misaki, K., Ohkubo, H., Ono, Y. Brain Res. Mol. Brain Res. (1999) [Pubmed]
  5. NEUROD1 acts in vitro as an upstream regulator of NEUROD2 in trophoblast cells. Westerman, B.A., Chhatta, A., Poutsma, A., van Vegchel, T., Oudejans, C.B. Biochim. Biophys. Acta (2004) [Pubmed]
  6. Identification and analysis of the promoter region of the human NeuroD-related factor (NDRF)1. Kitamura, T., Miyachi, T., Nakamura, S., Kawakami, H. Biochim. Biophys. Acta (1999) [Pubmed]
 
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