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Gene Review

MIS12  -  MIS12 kinetochore complex component

Homo sapiens

Synonyms: 2510025F08Rik, KNTC2AP, MGC2488, MTW1, Protein MIS12 homolog, ...
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High impact information on MIS12


Biological context of MIS12


  1. A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. Obuse, C., Iwasaki, O., Kiyomitsu, T., Goshima, G., Toyoda, Y., Yanagida, M. Nat. Cell Biol. (2004) [Pubmed]
  2. The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. Kline, S.L., Cheeseman, I.M., Hori, T., Fukagawa, T., Desai, A. J. Cell Biol. (2006) [Pubmed]
  3. Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. Goshima, G., Kiyomitsu, T., Yoda, K., Yanagida, M. J. Cell Biol. (2003) [Pubmed]
  4. The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore. Goshima, G., Iwasaki, O., Obuse, C., Yanagida, M. EMBO J. (2003) [Pubmed]
  5. Characterization of a Mis12 homologue in Arabidopsis thaliana. Sato, H., Shibata, F., Murata, M. Chromosome Res. (2005) [Pubmed]
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