Gene Review:
CENPA - centromere protein A
Homo sapiens
Synonyms:
CENP-A, CenH3, Centromere autoantigen A, Centromere protein A, Histone H3-like centromeric protein A
Busch,
Lampson,
Yoda,
Houmura,
Brinkley,
Pendón,
Shah,
Van Hooser,
Iglesias,
Ortíz,
Hashimoto,
Busch,
Valdivia,
Brinkley,
Fukuda,
Morishita,
Himeno,
Figueroa,
Kapoor,
Shimada,
Turner,
Zeng,
Ochiai,
Takeyasu,
Tomonaga,
Okazaki,
Ouspenski,
Nomura,
Zhong,
Oohashi,
Matsushita,
Yoda,
Valdivia,
He,
Woods,
Foltz,
Cleveland,
Ando,
Yamaguchi,
Black,
Maddox,
Jansen,
Desai,
Sugimoto,
Figueroa,
- Overexpression and mistargeting of centromere protein-A in human primary colorectal cancer. Tomonaga, T., Matsushita, K., Yamaguchi, S., Oohashi, T., Shimada, H., Ochiai, T., Yoda, K., Nomura, F. Cancer Res. (2003)
- A novel centromere monospecific serum to a human autoepitope on the histone H3-like protein CENP-A. Valdivia, M.M., Figueroa, J., Iglesias, C., Ortíz, M. FEBS Lett. (1998)
- Development of a CENP-A/CENP-B-specific immune response in a patient with systemic sclerosis. Mahler, M., Mierau, R., Genth, E., Blüthner, M. Arthritis Rheum. (2002)
- Molecular cloning and sequence analysis of hamster CENP-A cDNA. Figueroa, J., Pendón, C., Valdivia, M.M. BMC Genomics (2002)
- Detection of anticentromere antibodies using recombinant human CENP-A protein. Sun, D., Martinez, A., Sullivan, K.F., Sharp, G.C., Hoch, S.O. Arthritis Rheum. (1996)
- Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres. Hayashi, T., Fujita, Y., Iwasaki, O., Adachi, Y., Takahashi, K., Yanagida, M. Cell (2004)
- Kinetochore-spindle microtubule interactions during mitosis. Kline-Smith, S.L., Sandall, S., Desai, A. Curr. Opin. Cell Biol. (2005)
- Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain. Black, B.E., Jansen, L.E., Maddox, P.S., Foltz, D.R., Desai, A.B., Shah, J.V., Cleveland, D.W. Mol. Cell (2007)
- The human CENP-A centromeric nucleosome-associated complex. Foltz, D.R., Jansen, L.E., Black, B.E., Bailey, A.O., Yates, J.R., Cleveland, D.W. Nat. Cell Biol. (2006)
- CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis. Zeitlin, S.G., Shelby, R.D., Sullivan, K.F. J. Cell Biol. (2001)
- Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells. Liu, S.T., Rattner, J.B., Jablonski, S.A., Yen, T.J. J. Cell Biol. (2006)
- CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function. Kunitoku, N., Sasayama, T., Marumoto, T., Zhang, D., Honda, S., Kobayashi, O., Hatakeyama, K., Ushio, Y., Saya, H., Hirota, T. Dev. Cell (2003)
- CENP-G: a new centromeric protein that is associated with the alpha-1 satellite DNA subfamily. He, D., Zeng, C., Woods, K., Zhong, L., Turner, D., Busch, R.K., Brinkley, B.R., Busch, H. Chromosoma (1998)
- Centromere/kinetochore localization of human centromere protein A (CENP-A) exogenously expressed as a fusion to green fluorescent protein. Sugimoto, K., Fukuda, R., Himeno, M. Cell Struct. Funct. (2000)
- Relevance of histone acetylation and replication timing for deposition of centromeric histone CENP-A. Ouspenski, I.I., Van Hooser, A.A., Brinkley, B.R. Exp. Cell Res. (2003)
- Epigenetic assembly of centromeric chromatin at ectopic alpha-satellite sites on human chromosomes. Nakano, M., Okamoto, Y., Ohzeki, J., Masumoto, H. J. Cell. Sci. (2003)
- H2A.Z contributes to the unique 3D structure of the centromere. Greaves, I.K., Rangasamy, D., Ridgway, P., Tremethick, D.J. Proc. Natl. Acad. Sci. U.S.A. (2007)
- The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Lampson, M.A., Kapoor, T.M. Nat. Cell Biol. (2005)
- Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. Lam, A.L., Boivin, C.D., Bonney, C.F., Rudd, M.K., Sullivan, B.A. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. Fujita, Y., Hayashi, T., Kiyomitsu, T., Toyoda, Y., Kokubu, A., Obuse, C., Yanagida, M. Dev. Cell (2007)
- CENP-A, -B, and -C chromatin complex that contains the I-type alpha-satellite array constitutes the prekinetochore in HeLa cells. Ando, S., Yang, H., Nozaki, N., Okazaki, T., Yoda, K. Mol. Cell. Biol. (2002)
- The constitutive centromere component CENP-50 is required for recovery from spindle damage. Minoshima, Y., Hori, T., Okada, M., Kimura, H., Haraguchi, T., Hiraoka, Y., Bao, Y.C., Kawashima, T., Kitamura, T., Fukagawa, T. Mol. Cell. Biol. (2005)
- Assembly of additional heterochromatin distinct from centromere-kinetochore chromatin is required for de novo formation of human artificial chromosome. Nakashima, H., Nakano, M., Ohnishi, R., Hiraoka, Y., Kaneda, Y., Sugino, A., Masumoto, H. J. Cell. Sci. (2005)
- Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Klein, U.R., Nigg, E.A., Gruneberg, U. Mol. Biol. Cell (2006)
- Human centromere protein A (CENP-A) can replace histone H3 in nucleosome reconstitution in vitro. Yoda, K., Ando, S., Morishita, S., Houmura, K., Hashimoto, K., Takeyasu, K., Okazaki, T. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Assembly of CENP-A into centromeric chromatin requires a cooperative array of nucleosomal DNA contact sites. Shelby, R.D., Vafa, O., Sullivan, K.F. J. Cell Biol. (1997)
- CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA. Ohzeki, J., Nakano, M., Okada, T., Masumoto, H. J. Cell Biol. (2002)
- The centromere protein CENP-B behaves as a microtubule-associated protein. Armas-Portela, R., Kremer, L., Avila, J. Acta Histochem. Suppl. (1991)