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Gene Review

Renbp  -  renin binding protein

Rattus norvegicus

Synonyms: AGE, GlcNAc 2-epimerase, N-acetyl-D-glucosamine 2-epimerase, N-acylglucosamine 2-epimerase, Renin-binding protein, ...
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Disease relevance of Renbp


High impact information on Renbp


Biological context of Renbp


Associations of Renbp with chemical compounds

  • On sodium depletion and captopril administration, the rat showed a marked increase in the adrenal RnBP mRNA level and a slight decrease in the kidney RnBP mRNA level [1].

Other interactions of Renbp


Analytical, diagnostic and therapeutic context of Renbp

  • In situ hybridization for renin mRNA was carried out using digoxygenin-labelled antisense oligonucleotides and for RnBP using labelled antisense oligonucleotides and an antisense riboprobe [2].


  1. Tissue-specific regulation of renin-binding protein gene expression in rats. Tada, M., Takahashi, S., Miyano, M., Miyake, Y. J. Biochem. (1992) [Pubmed]
  2. The expression of renin-binding protein and renin in the kidneys of rats with two-kidney one-clip hypertension. Leckie, B.J., Lacy, P.S., Lidder, S. J. Hypertens. (2000) [Pubmed]
  3. The metabolism of sialic acids in isolated rat colonic mucosal cells. Corfield, A.P., Clamp, J.R., Wagner, S.A. Biochem. J. (1985) [Pubmed]
  4. Identification of a domain conferring nucleotide binding to the N-acetyl-d-glucosamine 2-epimerase (Renin binding protein). Takahashi, S., Ogasawara, H., Takahashi, K., Hori, K., Saito, K., Mori, K. J. Biochem. (2002) [Pubmed]
  5. Genetic and molecular properties of human and rat renin-binding proteins with reference to the function of the leucine zipper motif. Inoue, H., Takahashi, S., Fukui, K., Miyake, Y. J. Biochem. (1991) [Pubmed]
  6. Assignment of the gene encoding renin binding protein (Renbp) to rat chromosome Xq37 by in situ hybridization and radiation hybrid mapping. Zürcher, H., Van Vooren, P., Szpirer, J., Szpirer, C., Kreutz, R. Cytogenet. Genome Res. (2002) [Pubmed]
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