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Gene Review

PP5.2  -  serine/threonine-protein phosphatase 5

Arabidopsis thaliana

Synonyms: Arabidopsis thaliana protein phosphatase 5, AtPP5, F7D19.19, F7D19_19, PAPP5, ...
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High impact information on PAPP5/PP5


Biological context of PAPP5/PP5

  • Alternative splicing results in a larger transcript containing an additional exon encoding two putative transmembrane domains and, hence, in a larger PP5 isoform [3].

Anatomical context of PAPP5/PP5

  • Production of yellow fluorescent protein-PP5 chimeras in plant cells indicated that the 55-kD isoform is localized in both the nucleus and the cytoplasm, whereas the 62-kD isoform is targeted to the endoplasmic reticulum, including the nuclear envelope [3].

Associations of PAPP5/PP5 with chemical compounds


  1. Phytochrome-specific type 5 phosphatase controls light signal flux by enhancing phytochrome stability and affinity for a signal transducer. Ryu, J.S., Kim, J.I., Kunkel, T., Kim, B.C., Cho, D.S., Hong, S.H., Kim, S.H., Fernández, A.P., Kim, Y., Alonso, J.M., Ecker, J.R., Nagy, F., Lim, P.O., Song, P.S., Schäfer, E., Nam, H.G. Cell (2005) [Pubmed]
  2. Heat shock protein 90 and its co-chaperone protein phosphatase 5 interact with distinct regions of the tomato I-2 disease resistance protein. de la Fuente van Bentem, S., Vossen, J.H., de Vries, K.J., van Wees, S., Tameling, W.I., Dekker, H.L., de Koster, C.G., Haring, M.A., Takken, F.L., Cornelissen, B.J. Plant J. (2005) [Pubmed]
  3. The subcellular localization of plant protein phosphatase 5 isoforms is determined by alternative splicing. de la Fuente van Bentem, S., Vossen, J.H., Vermeer, J.E., de Vroomen, M.J., Gadella, T.W., Haring, M.A., Cornelissen, B.J. Plant Physiol. (2003) [Pubmed]
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