Disease relevance of BZX

• Bazex syndrome is a paraneoplastic condition that is most frequently associated with squamous cell carcinoma of the upper aerodigestive tract [1].
• Follicular atrophoderma and basal cell carcinomas: the Bazex syndrome [2].
• The patients were reminiscent of Bazex syndrome; however, ichthyosis is not a component of Bazex syndrome [3].
• We report a patient with Bazex syndrome with predominantly bullous lesions that mimicked a primary autoimmune bullous disorder [1].
• Overlap between the Bazex syndrome and congenital hypotrichosis and milia [4].

High impact information on BZX

• Follicular atrophoderma is a rare anomaly observed mainly in the X-dominant form of chondrodysplasia punctata (Conradi-Hünermann-Happle syndrome) and in the X-linked dominant Bazex syndrome [3].
• Acrokeratosis paraneoplastica (Bazex syndrome) occurring with acquired ichthyosis in Hodgkin's disease [5].
• We report a case of acrokeratosis paraneoplastica (AP; Bazex syndrome), characterized by typical palmoplantar hyperkeratosis and psoriasiform scaly erythema of the acral regions, associated with primary cutaneous squamous cell carcinoma (SCC) on the left lower leg [6].
• Acrokeratosis paraneoplastica (Bazex syndrome) associated with primary cutaneous squamous cell carcinoma of the lower leg, vitiligo and alopecia areata [6].
• Acrokeratosis paraneoplastica (Bazex syndrome) with adenocarcinoma of the colon: report of a case and review of the literature [7].

Anatomical context of BZX

• Acrokeratosis paraneoplastica (Bazex syndrome) preceeding the diagnosis of metastatic squamous cell carcinoma of the esophagus [8].
• Acrokeratosis paraneoplastica (Bazex syndrome) is a rare but distinctive dermatosis associated with carcinomas of the upper aerodigestive tract with possible cervical lymph node metastases [9].

Other interactions of BZX

• The association of skin cancers with other abnormalities is found in nevoid basal cell carcinoma syndrome, Bazex syndrome, Rombo syndrome, xeroderma pigmentosum, dysplastic nevus syndrome, and epidermodysplasia verruciformis [10].

Analytical, diagnostic and therapeutic context of BZX

• Bullous lesions in Bazex syndrome and successful treatment with oral psoralen phototherapy [11].

References